The emerging role of T follicular helper (T
Aging
Atherosclerosis
Autoimmunity
Cancer
Inflammaging
T follicular helper cells
T follicular regulatory cells
Journal
Ageing research reviews
ISSN: 1872-9649
Titre abrégé: Ageing Res Rev
Pays: England
ID NLM: 101128963
Informations de publication
Date de publication:
08 2020
08 2020
Historique:
received:
30
01
2020
revised:
03
04
2020
accepted:
08
04
2020
pubmed:
29
4
2020
medline:
15
12
2020
entrez:
29
4
2020
Statut:
ppublish
Résumé
The world population is undergoing a rapid expansion of older adults. Aging is associated with numerous changes that affect all organs and systems, including every component of the immune system. Immunosenescence is a multifaceted process characterized by poor response to vaccine and higher incidence of bacterial and viral infections, cancer, cardiovascular and autoimmune diseases. Immunosenescence has been associated with chronic low-grade inflammation referred to as inflammaging, whose underlying mechanisms remain incompletely elucidated, including age-related changes affecting components of the innate and adaptive immune system. T follicular helper (T
Identifiants
pubmed: 32344191
pii: S1568-1637(20)30047-7
doi: 10.1016/j.arr.2020.101071
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
101071Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.