Fulminant Emphysematous Pyelonephritis by Candida glabrata in a Kidney Allograft.
Candida glabrata
Candiduria
Diabetes mellitus
Empagliflozin
Fungal pyelonephritis
Kidney transplant
Urinary tract infection
Journal
Nephron
ISSN: 2235-3186
Titre abrégé: Nephron
Pays: Switzerland
ID NLM: 0331777
Informations de publication
Date de publication:
2020
2020
Historique:
received:
12
02
2020
accepted:
14
03
2020
pubmed:
29
4
2020
medline:
8
7
2021
entrez:
29
4
2020
Statut:
ppublish
Résumé
Emphysematous pyelonephritis (EPN) is a rare and serious necrotizing infection that is potentially life-threatening. It has been seldom reported in kidney grafts and is usually caused by Gram-negative bacteria, with some case reports caused by anaerobic bacteria, and has been closely associated with poorly controlled diabetes mellitus (DM) and urinary tract structural abnormalities. There are no reports of EPN of fungal etiology in kidney grafts. We present a case of a 53-year-old kidney transplant recipient with a history of DM, active vesicoureteral reflux, and recurrent urinary tract infections who developed EPN in the kidney allograft caused by Candida glabrata, 3 weeks after starting treatment with empagliflozin, with an aggressive course that required urgent transplant nephrectomy.
Identifiants
pubmed: 32344404
pii: 000507259
doi: 10.1159/000507259
doi:
Substances chimiques
Benzhydryl Compounds
0
Glucosides
0
empagliflozin
HDC1R2M35U
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
304-309Informations de copyright
© 2020 S. Karger AG, Basel.