Esophageal Pressure Versus Gas Exchange to Set PEEP During Intraoperative Ventilation.


Journal

Respiratory care
ISSN: 1943-3654
Titre abrégé: Respir Care
Pays: United States
ID NLM: 7510357

Informations de publication

Date de publication:
May 2020
Historique:
entrez: 30 4 2020
pubmed: 30 4 2020
medline: 29 1 2021
Statut: ppublish

Résumé

Pneumoperitoneum and Trendelenburg position affect respiratory system mechanics and oxygenation during elective pelvic robotic surgery. The primary aim of this randomized pilot study was to compare the effects of a conventional low tidal volume ventilation with PEEP guided by gas exchange (V This study was conducted in a single-center tertiary hospital between September 2017 and January 2019. Forty-nine adult patients scheduled for elective pelvic robotic surgery were screened; 28 subjects completed the full analysis. Exclusion criteria were American Society of Anesthesiologists physical status ≥ 3, contraindications to nasogastric catheter placement, and pregnancy. After dedicated naso/orogastric catheter insertion, subjects were randomly assigned to V Compared to V Oxygenation and respiratory system mechanics were improved when applying a ventilatory strategy tailoring PEEP to equalize expiratory transpulmonary pressure in subjects undergoing pelvic robotic surgery compared to a V

Sections du résumé

BACKGROUND BACKGROUND
Pneumoperitoneum and Trendelenburg position affect respiratory system mechanics and oxygenation during elective pelvic robotic surgery. The primary aim of this randomized pilot study was to compare the effects of a conventional low tidal volume ventilation with PEEP guided by gas exchange (V
METHODS METHODS
This study was conducted in a single-center tertiary hospital between September 2017 and January 2019. Forty-nine adult patients scheduled for elective pelvic robotic surgery were screened; 28 subjects completed the full analysis. Exclusion criteria were American Society of Anesthesiologists physical status ≥ 3, contraindications to nasogastric catheter placement, and pregnancy. After dedicated naso/orogastric catheter insertion, subjects were randomly assigned to V
RESULTS RESULTS
Compared to V
CONCLUSIONS CONCLUSIONS
Oxygenation and respiratory system mechanics were improved when applying a ventilatory strategy tailoring PEEP to equalize expiratory transpulmonary pressure in subjects undergoing pelvic robotic surgery compared to a V

Identifiants

pubmed: 32345760
pii: respcare.07238
doi: 10.4187/respcare.07238
doi:

Banques de données

ClinicalTrials.gov
['NCT03153592']

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

625-635

Informations de copyright

Copyright © 2020 by Daedalus Enterprises.

Déclaration de conflit d'intérêts

Dr Mojoli discloses relationships with Hamilton Medical and GE Healthcare. The other authors have no conflicts to disclose.

Auteurs

Gianmaria Cammarota (G)

Department of Anesthesiology and Intensive Care, Maggiore della Carità University Hospital, Novara, Italy. gmcamma@gmail.com.

Gianluigi Lauro (G)

Department of Translational Medicine, Eastern Piedmont University, Novara, Italy.

Ilaria Sguazzotti (I)

Department of Translational Medicine, Eastern Piedmont University, Novara, Italy.

Iolanda Mariano (I)

Department of Translational Medicine, Eastern Piedmont University, Novara, Italy.

Raffaella Perucca (R)

Department of Anesthesiology and Intensive Care, Maggiore della Carità University Hospital, Novara, Italy.

Antonio Messina (A)

Department of Anesthesiology and Intensive Care, Humanitas Research Hospital, Milan, Italy.

Marta Zanoni (M)

Department of Anesthesiology and Intensive Care, Maggiore della Carità University Hospital, Novara, Italy.

Eugenio Garofalo (E)

Department of Medical and Surgical Science, Magna Graecia University, Catanzaro, Italy.

Andrea Bruni (A)

Department of Medical and Surgical Science, Magna Graecia University, Catanzaro, Italy.

Francesco Della Corte (F)

Department of Translational Medicine, Eastern Piedmont University, Novara, Italy.

Paolo Navalesi (P)

Department of Medical and Surgical Science, Magna Graecia University, Catanzaro, Italy.

Elena Bignami (E)

Anesthesiology, Critical Care and Pain Medicine Division, Department of Medicine and Surgery. University of Parma, Parma, Italy.

Rosanna Vaschetto (R)

Department of Translational Medicine, Eastern Piedmont University, Novara, Italy.

Francesco Mojoli (F)

Anesthesia and Intensive Care Department, Policlinico S. Matteo IRCCS Foundation, Pavia, Italy.

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Classifications MeSH