Seroepidemiology of hepatitis E virus infection in patients undergoing maintenance hemodialysis: Systematic review and meta-analysis.


Journal

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
ISSN: 1744-9987
Titre abrégé: Ther Apher Dial
Pays: Australia
ID NLM: 101181252

Informations de publication

Date de publication:
Feb 2021
Historique:
received: 01 03 2020
revised: 28 03 2020
accepted: 24 04 2020
pubmed: 30 4 2020
medline: 8 10 2021
entrez: 30 4 2020
Statut: ppublish

Résumé

Patients undergoing regular hemodialysis (HD) are at an extreme risk of acquiring bloodstream infections compared to the general population. Hepatitis E virus (HEV) infection is an important emerging health issue in these patients. To date, numerous studies have investigated the seroprevalence of HEV among HD patients across the world; however, the data are conflicting. The present study aimed to measure the exposure rate of HD patients to HEV infection by estimating the overall seroprevalence of HEV in this high-risk group. A systematic literature search was carried out using five electronic databases from inception to January 10, 2020, with standard keywords. Pooled seroprevalence estimates with 95% confidence intervals (CIs) were calculated using a random intercept logistic regression model. The seroprevalence of HEV increased from 6.6% between the years of 1994 and 2000 to 11.13% from 2016 to 2020. Blood transfusion was associated with a nearly 2-fold increase in the rate of HEV seropositivity (OR = 1.99; 95% CI: 1.50-2.63, P < .0001, I

Identifiants

pubmed: 32348032
doi: 10.1111/1744-9987.13507
doi:

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

4-15

Informations de copyright

© 2020 International Society for Apheresis, Japanese Society for Apheresis, and Japanese Society for Dialysis Therapy.

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Auteurs

Ahmad Tavakoli (A)

Department of Medical Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Seyed Moayed Alavian (SM)

Baqiyatallah Research Center for Gastroenterology and Liver Diseases (BRCGL), Baqiyatallah University of Medical Sciences, Tehran, Iran.
Middle East Liver Disease (MELD) Center, Tehran, Iran.

Mohsen Moghoofei (M)

Department of Microbiology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Medical Biology Research Center, Institute of Health and Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Shayan Mostafaei (S)

Medical Biology Research Center, Institute of Health and Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Epidemiology and Biostatistics Unit, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Saeedeh Abbasi (S)

Department of Medical Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Mohammad Farahmand (M)

Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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