Myocardial ischemia: From disease to syndrome.

Angina Chronic coronary syndromes Coronary artery disease Ischemic heart disease Microvascular dysfunction

Journal

International journal of cardiology
ISSN: 1874-1754
Titre abrégé: Int J Cardiol
Pays: Netherlands
ID NLM: 8200291

Informations de publication

Date de publication:
01 09 2020
Historique:
received: 20 04 2020
revised: 24 04 2020
accepted: 24 04 2020
pubmed: 30 4 2020
medline: 15 5 2021
entrez: 30 4 2020
Statut: ppublish

Résumé

Although current guidelines on the management of stable coronary artery disease acknowledge that multiple mechanisms may precipitate myocardial ischemia, recommended diagnostic, prognostic and therapeutic algorithms are still focused on obstructive epicardial atherosclerotic lesions, and little progress has been made in identifying management strategies for non-atherosclerotic causes of myocardial ischemia. The purpose of this consensus paper is three-fold: 1) to marshal scientific evidence that obstructive atherosclerosis can co-exist with other mechanisms of ischemic heart disease (IHD); 2) to explore how the awareness of multiple precipitating mechanisms could impact on pre-test probability, provocative test results and treatment strategies; and 3) to stimulate a more comprehensive approach to chronic myocardial ischemic syndromes, consistent with the new understanding of this condition.

Identifiants

pubmed: 32348810
pii: S0167-5273(20)32112-4
doi: 10.1016/j.ijcard.2020.04.074
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

32-35

Informations de copyright

Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors report no relationships that could be construed as a conflict of interest.

Auteurs

Mario Marzilli (M)

Department of Surgery, Medical, Molecular and Critical Area Pathology, University of Pisa, Italy. Electronic address: mario.marzilli@med.unipi.it.

Filippo Crea (F)

Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy.

Doralisa Morrone (D)

Department of Surgery, Medical, Molecular and Critical Area Pathology, University of Pisa, Italy.

Robert O Bonow (RO)

Department of Medicine, Northwestern University, Chicago, IL, USA.

David L Brown (DL)

Cardiovascular Division, Washington University School of Medicine, St Louis, MO, USA.

Paolo G Camici (PG)

Vita salute University and San Raffaele Hospital, Milan, Italy.

William M Chilian (WM)

Department of Integrative Medical Sciences, Northeast Ohio Medical University, Rootstown, OH, United States of America.

Anthony DeMaria (A)

Division of Cardiology, University of California, San Diego, San Diego, CA, USA.

Giacinta Guarini (G)

Department of Surgery, Medical, Molecular and Critical Area Pathology, University of Pisa, Italy.

Alda Huqi (A)

Department of Surgery, Medical, Molecular and Critical Area Pathology, University of Pisa, Italy.

C Noel Bairey Merz (CNB)

Barbra Streisand Women's Heart Center, Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, USA.

Carl Pepine (C)

Division of Cardiology, Department of Medicine, University of Florida, Gainesville, USA.

Maria Chiara Scali (MC)

Department of Surgery, Medical, Molecular and Critical Area Pathology, University of Pisa, Italy.

William S Weintraub (WS)

Outcomes Research, MedStar Heart & Vascular Institute, MedStar Washington Hospital Center, USA.

William E Boden (WE)

VA New England Health Care System, Boston, MA, USA.

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Classifications MeSH