Severe obstructive sleep apnea is associated with coronary microvascular dysfunction and obstruction in patients with ST-elevation myocardial infarction.

Cardiovascular magnetic resonance imaging ST-segment elevation myocardial infarction coronary microvascular dysfunction and obstruction microvascular obstruction obstructive sleep apnea

Journal

European heart journal. Acute cardiovascular care
ISSN: 2048-8734
Titre abrégé: Eur Heart J Acute Cardiovasc Care
Pays: England
ID NLM: 101591369

Informations de publication

Date de publication:
30 Apr 2020
Historique:
entrez: 1 5 2020
pubmed: 1 5 2020
medline: 1 5 2020
Statut: aheadofprint

Résumé

Coronary microvascular dysfunction and obstruction (CMVO) is a strong predictor of a poor prognosis in patients with ST-segment elevation myocardial infarction (STEMI). Although research has suggested that obstructive sleep apnea (OSA) exacerbates CMVO after primary percutaneous coronary intervention, data supporting a correlation between OSA and CMVO are limited. This study was performed to investigate whether OSA is associated with CMVO, detected as microvascular obstruction on cardiovascular magnetic resonance images, in patients with STEMI. Patients ( The REI was significantly higher in the presence of microvascular obstruction ( Severe OSA was associated with CMVO after primary percutaneous coronary intervention in patients with STEMI.

Sections du résumé

BACKGROUND BACKGROUND
Coronary microvascular dysfunction and obstruction (CMVO) is a strong predictor of a poor prognosis in patients with ST-segment elevation myocardial infarction (STEMI). Although research has suggested that obstructive sleep apnea (OSA) exacerbates CMVO after primary percutaneous coronary intervention, data supporting a correlation between OSA and CMVO are limited. This study was performed to investigate whether OSA is associated with CMVO, detected as microvascular obstruction on cardiovascular magnetic resonance images, in patients with STEMI.
METHODS METHODS
Patients (
RESULTS RESULTS
The REI was significantly higher in the presence of microvascular obstruction (
CONCLUSION CONCLUSIONS
Severe OSA was associated with CMVO after primary percutaneous coronary intervention in patients with STEMI.

Identifiants

pubmed: 32349515
doi: 10.1177/2048872620919946
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2048872620919946

Auteurs

Yoshitaka Ichikawa (Y)

Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Japan.

Yasuhiro Izumiya (Y)

Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Japan.

Koichi Tamita (K)

Department of Cardiovascular Medicine, Nishinomiya Watanabe Cardiovascular Center, Japan.

Hiroya Hayashi (H)

Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Japan.

Hirotoshi Ishikawa (H)

Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Japan.

Atsushi Shibata (A)

Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Japan.

Atsushi Yamamuro (A)

Department of Cardiovascular Medicine, Nishinomiya Watanabe Cardiovascular Center, Japan.

Minoru Yoshiyama (M)

Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, Japan.

Classifications MeSH