Yttrium-90 Synovectomy in Hemophilic Arthropathy: An Institutional Experience for 15 Years.
Bleeding episodes
hemophilic joints
yttrium synovectomy
Journal
Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
ISSN: 0972-3919
Titre abrégé: Indian J Nucl Med
Pays: India
ID NLM: 8901274
Informations de publication
Date de publication:
Historique:
received:
07
08
2019
revised:
09
10
2019
accepted:
18
10
2019
entrez:
1
5
2020
pubmed:
1
5
2020
medline:
1
5
2020
Statut:
ppublish
Résumé
The objective of this study is to assess the efficacy of Yttrium-90 (Y-90) radiation synovectomy in decreasing the recurrent bleeding episodes in hemophilic joints. A retrospective analysis of patients who had Y-90 synovectomy from January 2001 to January 2016 was done. Among them, patients with minimum follow-up of 6 months were selected. The response in terms of decrease in the number of bleeding episodes was evaluated. A total of 167 patients (243 joints) with hemophilia had radiation synovectomy over 15 years. Those with a minimum follow-up of 6 months were 155 joints (115 patients). The age ranged from 5 to 43 years and included 113 male and two female patients. Data for 11 joints were unavailable as these patients were lost to follow-up. The assessment of response for the remaining 144 joints was done based on the data available for different follow-up periods. They were divided into the following - 7 months to 2 years (89 joints), 3-5 years (6 joints), 6-10 years (39 joints), and above 11 years (10 joints). Overall, 37.4% of the joints had complete response, 56% had partial response, and 6% of the joints had no response. Radiation synovectomy is a noninvasive and effective modality which decreases the bleeding episodes in hemophiliac joints and improves the quality of life remarkably.
Identifiants
pubmed: 32351269
doi: 10.4103/ijnm.IJNM_141_19
pii: IJNM-35-143
pmc: PMC7182316
doi:
Types de publication
Journal Article
Langues
eng
Pagination
143-146Informations de copyright
Copyright: © 2020 Indian Journal of Nuclear Medicine.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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