Understanding buckwheat allergies for the management of allergic reactions in humans and animals.

allergen component allergen molecules anaphylaxis buckwheat allergen buckwheat allergy component-resolved diagnosis

Journal

Breeding science
ISSN: 1344-7610
Titre abrégé: Breed Sci
Pays: Japan
ID NLM: 9888571

Informations de publication

Date de publication:
Mar 2020
Historique:
received: 01 04 2019
accepted: 14 11 2019
entrez: 1 5 2020
pubmed: 1 5 2020
medline: 1 5 2020
Statut: ppublish

Résumé

Buckwheat allergy is an immediate hypersensitivity reaction that includes anaphylaxis mediated by specific IgE antibodies. Several IgE-binding proteins in common buckwheat have been reported to be possible clinically relevant buckwheat allergens. Although common buckwheat is popularly consumed in Asia, buckwheat allergy is becoming a serious problem not only in Asia but also in Europe. In addition, common buckwheat has also been found to be a causative agent of allergic symptoms in animals. In recent years, in addition to conventional food allergy testing methods, the development of component-resolved diagnosis (CRD) has improved the diagnostic accuracy of food allergy. The identification of allergens is essential for the construction of CRD. In this review, we introduce the different types of buckwheat allergens and discuss how each buckwheat allergen contributes to the diagnosis of buckwheat allergy. We also present the analysis of buckwheat allergen that will help reduce the allergenicity of common buckwheat and reduce buckwheat allergen molecules. These findings may be beneficial in overcoming buckwheat allergies in humans and animals.

Identifiants

pubmed: 32351307
doi: 10.1270/jsbbs.19051
pii: JST.JSTAGE/jsbbs/19051
pmc: PMC7180145
doi:

Types de publication

Journal Article

Langues

eng

Pagination

85-92

Informations de copyright

Copyright © 2020 by JAPANESE SOCIETY OF BREEDING.

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Auteurs

Rie Satoh (R)

Functionality Evaluation Unit, Division of Food Function Research, Food Research Institute, National Agriculture and Food Research Organization, 2-1-12 Kannondai, Tsukuba, Ibaraki 305-8642, Japan.

Erika Jensen-Jarolim (E)

Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
The Interuniversity Messerli Research Institute, University of Veterinary Medicine Vienna, Medical University Vienna, University of Vienna, Veterinaerplatz 1, 1210, Vienna, Austria.

Reiko Teshima (R)

Division of Food Safety, Faculty of Veterinary Medicine, Okayama University of Sciences, 1-3 Ikoinooka, Imabari, Ehime 794-8555, Japan.

Classifications MeSH