Trends in the Retinal Nerve Fiber Layer Thickness Changes with Different Degrees of Visual Field Defects.
Journal
Journal of ophthalmology
ISSN: 2090-004X
Titre abrégé: J Ophthalmol
Pays: United States
ID NLM: 101524199
Informations de publication
Date de publication:
2020
2020
Historique:
received:
03
01
2020
revised:
08
03
2020
accepted:
24
03
2020
entrez:
1
5
2020
pubmed:
1
5
2020
medline:
1
5
2020
Statut:
epublish
Résumé
To explore the disease progression of primary open-angle glaucoma (POAG) in individuals with different degrees of VF defects by analyzing the trends in retinal nerve fiber layer (RNFL) changes at each stage. A total of 39 patients (77 eyes) were divided into three groups based on the severity of glaucomatous visual field (VF) loss: the first group included patients with mild baseline VF defects (mild group; The mean RNFL thickness was recorded for all the visits. Using simple linear regression analysis, we found that the The rate of RNFL thinning is linear; RNFL thinning is the fastest in individuals with mild baseline VF defects, followed by those with moderate baseline VF defects. In individuals with severe VF defects, changes in the RNFL thickness do not appropriately reflect the progression of the disease. The clinical trial is registered with ChiCTR2000028975.
Identifiants
pubmed: 32351723
doi: 10.1155/2020/4874876
pmc: PMC7174924
doi:
Types de publication
Journal Article
Langues
eng
Pagination
4874876Informations de copyright
Copyright © 2020 Wenhui Geng et al.
Déclaration de conflit d'intérêts
The authors declare that they have no conflicts of interest.
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