Abnormal blood-brain barrier water exchange in chronic multiple sclerosis lesions: A preliminary study.
Blood-brain barrier (BBB)
IDEALS
Relapsing-remitting multiple sclerosis (RRMS)
Water extraction fraction
Water permeability surface area product
Journal
Magnetic resonance imaging
ISSN: 1873-5894
Titre abrégé: Magn Reson Imaging
Pays: Netherlands
ID NLM: 8214883
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
11
02
2020
revised:
24
04
2020
accepted:
25
04
2020
pubmed:
1
5
2020
medline:
29
1
2021
entrez:
1
5
2020
Statut:
ppublish
Résumé
Relapsing-remitting multiple sclerosis (RRMS) is associated with persistent blood-brain barrier (BBB) dysfunction. The impact of this persistent dysfunction in both active and chronic MS lesions has yet to be investigated due to technological challenges associated with invasive assessment of BBB water transportation (e.g.
Identifiants
pubmed: 32353529
pii: S0730-725X(20)30075-8
doi: 10.1016/j.mri.2020.04.017
pii:
doi:
Substances chimiques
Water
059QF0KO0R
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
126-133Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.