LIPUS promotes synthesis and secretion of extracellular matrix and reduces cell apoptosis in human osteoarthritis through upregulation of SOX9 expression.

LIPUS apoptosis chondrocytes extracellular matrix osteoarthritis

Journal

International journal of clinical and experimental pathology
ISSN: 1936-2625
Titre abrégé: Int J Clin Exp Pathol
Pays: United States
ID NLM: 101480565

Informations de publication

Date de publication:
2020
Historique:
received: 24 01 2020
accepted: 06 03 2020
entrez: 2 5 2020
pubmed: 2 5 2020
medline: 2 5 2020
Statut: epublish

Résumé

Increasing studies have illustrated that low-intensity pulsed ultrasound (LIPUS) has a therapeutic effect in experimental animal models of osteoarthritis (OA). However, the function of the LIPUS on human chondrocytes of OA remains unclear. The aim of the current study was to observe the effect and explore the mechanism of LIPUS treatment on proliferation, apoptosis, and extracellular matrix (ECM) production of chondrocytes

Identifiants

pubmed: 32355531
pmc: PMC7191152

Types de publication

Journal Article

Langues

eng

Pagination

810-817

Informations de copyright

IJCEP Copyright © 2020.

Déclaration de conflit d'intérêts

None.

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Auteurs

Weizhong Ding (W)

Department of Orthopedic Surgery, The Second Affiliated Hospital, Chongqing Medical University Chongqing 400010, China.

Dengli Du (D)

Department of Orthopedic Surgery, The Second Affiliated Hospital, Chongqing Medical University Chongqing 400010, China.

Shirong Chen (S)

Department of Orthopedic Surgery, The Second Affiliated Hospital, Chongqing Medical University Chongqing 400010, China.

Classifications MeSH