Heavy menstrual bleeding in women with inherited bleeding disorders.
bleeding disorders
heavy menstrual bleeding
hormonal therapy
psychosocial
women
Journal
Haemophilia : the official journal of the World Federation of Hemophilia
ISSN: 1365-2516
Titre abrégé: Haemophilia
Pays: England
ID NLM: 9442916
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
31
08
2019
revised:
29
10
2019
accepted:
30
10
2019
entrez:
2
5
2020
pubmed:
2
5
2020
medline:
30
1
2021
Statut:
ppublish
Résumé
Heavy menstrual bleeding (HMB) is the commonest bleeding symptom among women with inherited bleeding disorders (IBD). Since HMB starts at the very onset of menarche and continues throughout the reproductive life, the health related quality of life of these women is affected and they are at an increased risk of developing iron-deficiency anemia. Because of the entrenched stigma and taboos, women and girls are often reluctant to discuss the problem of HMB within their families and do not seek medical advice. Increased awareness and multidisciplinary management approach for the management of these women are essential in ensuring an optimal outcome. It is important to take a careful history and undertake a thorough gynecological assessment to exclude other underlying/concomitant causes of HMB. Iron supplementation is essential. Strategies for decreasing menstrual blood flow are similar to those used for HMB in general with the addition of desmopressin and replacement therapy and the exclusion of non-steroidal anti-inflammatory drugs. Tranexamic acid and/or hormonal intervention are usually recommended as first-line therapy. Treatment choice should be individualized taking into account whether the woman wishes to preserve her fertility, if she requires contraception, the type of IBD, the severity of bleeding, and her social and religious background as well as acceptability and availability of the treatment options.
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
16-19Informations de copyright
© 2019 John Wiley & Sons Ltd.
Références
McLintock C. Women with bleeding disorders: clinical and psychological issues. Haemophilia. 2018;24(S6):20-24.
Chi C, Pollard D, Tuddenham EGD, Kadir RA. Menorrhagia in adolescents with inherited bleeding disorders. J Pediatr Adolesc Gynecol. 2010;23:215-222.
Kadir RA, Chi C. Women and von Willebrand disease: controversies in diagnosis and management. Semin Thromb Hemost. 2006;32(6):605-615.
Kadir RA, Economides DL, Sabin CA, Pollard D, Lee CA. Assessment of menstrual blood loss and gynaecological problems in patients with inherited bleeding disorders. Haemophilia. 1999;5(1):40-48.
Kirtava A, Drews C, Lally C, Dilley A, Evatt B. Medical, reproductive and psychosocial experiences of women diagnosed with von Willebrand disease receiving care in haemophilia treatment centres: a case-control study. Haemophilia. 2003;9:292-297.
The Lancet Child & Adolescent Health. Normalising menstruation, empowering girls. Lancet Child Adolec Health. 2018;2:379.
von Mackensen S. Quality of life in women with bleeding disorders. Haemophilia. 2011;17(Suppl1):33-37.
Matteson KA, Clark MA. Questioning our questions: do frequently asked questions adequately cover the aspects of women's lives most affected by abnormal uterine bleeding? Opinions of women with abnormal uterine bleeding participating in focus group discussions. Women Health. 2010;50:195-211.
Kadir RA, Edlund M, Von Mackensen S. The impact of menstrual disorders on quality of life in women with inherited bleeding disorders. Haemophilia. 2010;16:832-839.
Guterman M, Mehta P, Gibbs M. Menstrual taboos among major religions. Internet J World Health Soc Polit. 2007;5:1-7.
Bhartiya A. Menstruation, religion and society. Int J Social Sci Human. 2013;3:523-527.
Maybin JA, Critchley HO. Medical management of heavy menstrual bleeding. Women Health. 2016;12:27-34.
Edlund M. Nonhormonal treatments for heavy menstrual bleeding. J Womens Health. 2011;20(11):1645-1653.
O’Brien SH. Evaluation and management of heavy menstrual bleeding in adolescents: the role of the hematologist. Blood. 2018;132:2134-2142.
James AH, Kouides PA, Abdul-Kadir R, et al. Willebrand disease and other bleeding disorders in women: consensus on diagnosis and management from an international expert panel. Am J Obstet Gynecol. 2009;201:12.e1-8.
Chi C, Huq FY, Kadir RA. Levonorgestrel-releasing intrauterine system for the management of heavy menstrual bleeding in women with inherited bleeding disorders: long-term follow-up. Contraception. 2011;83:242-247.
Davies J, Kadir RA. Heavy menstrual bleeding: an update on management. Thromb Res. 2017;151(S1):70-77.
Joshi R, Khadlikar S, Patel M. Global trends in use of long-acting reversible and permanent methods of contraception: seeking a balance. Int J Gynaecol Obstet. 2015;131(S1):S60-S63.
Stewart A, Cummins C, Gold L, Jordan R, Phillips W. The effectiveness of the levonorgestrel-releasing intrauterine system in menorrhagia: a systematic review. Br J Obst Gynaecol. 2001;108:74-86.
Rimmer E, Jamieson MA, James P. Malposition and expulsion of the levonorgestrel intrauterine system among women with inherited bleeding disorders. Haemophilia. 2013;19:933-938.
Kadir RA, Chi C. Levonorgestrel intrauterine system: bleeding disorders and anticoagulant therapy. Contraception. 2007;75:S123-S129.
Wright KP, Johnson JV. Evaluation of extended and continuous use oral contraceptives. Ther Clin Risk Manag. 2008;4:905-911.
Matteson KA, Rahn DD, Wheeler TL, et al. Nonsurgical management of heavy menstrual bleeding: a systematic review. Obstet Gynecol. 2013;121:632-643.
Huq FY, Al-haderi M, Kadir RA. The outcome of endometrial ablation in women with inherited bleeding disorders. Haemophilia. 2012;18:413-420.
James A, Myers E, Cook C, Peitrobon R. Complications of hysterectomy in women with von Willebrand disease. Haemophilia. 2009;15:926-931.
Darwish M, Atlantis E, Mohamed-Taysir T. Psychological outcomes after hysterectomy for benign conditions: a systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2014;174:5-19.
Raza N, Waqas A, Jamal M. Post-operative anxiety, depression and psychiatric support in patients undergoing hysterectomy: a cross sectional survey. J Pak Med Assoc. 2015;65(4):443-445.