Spectrally dependent roll-off in visible-light optical coherence tomography.
Journal
Optics letters
ISSN: 1539-4794
Titre abrégé: Opt Lett
Pays: United States
ID NLM: 7708433
Informations de publication
Date de publication:
01 May 2020
01 May 2020
Historique:
entrez:
2
5
2020
pubmed:
2
5
2020
medline:
2
5
2020
Statut:
ppublish
Résumé
Recent development of visible-light optical coherence tomography (vis-OCT) has introduced new applications for noninvasive spectroscopic imaging. However, the measured spectra may be altered by spectrally dependent roll-off (SDR). We formulated a mathematical model for SDR that accounted for nonuniform wavenumber spacing, optical aberrations, and misalignments in the spectrometer. We simulated SDR based on this model and found strong agreement with measurements from a vis-OCT system. We verified that SDR altered spectroscopic measurements of fully oxygenated blood. We corrected these alterations by normalizing each spectrally dependent A-line by the measured SDR of the spectrometer. Our investigations of SDR are critical for informing OCT spectrometer design, alignment, and spectroscopic measurements.
Identifiants
pubmed: 32356845
pii: 431350
doi: 10.1364/OL.389240
pmc: PMC8194246
mid: NIHMS1702308
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2680-2683Subventions
Organisme : NEI NIH HHS
ID : R01 EY026078
Pays : United States
Organisme : NIDDK NIH HHS
ID : DP3 DK108248
Pays : United States
Organisme : NEI NIH HHS
ID : R44 EY026466
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY028304
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY029121
Pays : United States
Organisme : NEI NIH HHS
ID : T32 EY025202
Pays : United States
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