Renal malakoplakia mimicking a malignancy and diagnosed by fine-needle aspiration: A case report.


Journal

Diagnostic cytopathology
ISSN: 1097-0339
Titre abrégé: Diagn Cytopathol
Pays: United States
ID NLM: 8506895

Informations de publication

Date de publication:
Nov 2020
Historique:
received: 11 03 2020
accepted: 21 04 2020
pubmed: 3 5 2020
medline: 15 10 2021
entrez: 3 5 2020
Statut: ppublish

Résumé

Malakoplakia is a rare, granulomatous disease that affects a wide variety of organs and can have a clinical and radiographic presentation resembling that of malignancy. The genitourinary tract is the most commonly involved site. There are scant reported cases presenting as a locally advanced renal mass and even rarer, diagnosed by fine-needle aspiration (FNA) cytology. We report clinical, imaging, cytologic, and histological findings of an interesting case of malakoplakia initially diagnosed by FNA cytology. We also briefly review the literature and emphasize the importance of recognizing this entity when encountered in an aspirate material, which can help mitigate the diagnostic confusion of malakoplakia for clinicians.

Identifiants

pubmed: 32359126
doi: 10.1002/dc.24456
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1093-1097

Informations de copyright

© 2020 Wiley Periodicals, Inc.

Références

Stanton MJ, Maxted W. Malacoplakia: a study of the literature and current concepts of pathogenesis, diagnosis, and treatment. J Urol. 1981;125:139-146.
Biggar WD, Crawford L, Cardella C, Bear RA, Gladman D, Reynolds WJ. Malakoplakia and immunosuppressive therapy. Reversal of clinical and leukocyte abnormalities after withdrawal of prednisone and azathioprine. Am J Pathol. 1985;119:5-11.
Streem SB. Genitourinary malacoplakia in renal transplant recipients: pathogenic, prognostic and therapeutic considerations. J Urol. 1984;132:10-12.
Merritt AJ, Thiryayi SA, Rana DN. Malakoplakia diagnosed by fine needle aspiration (FNA) and liquid-based cytology (LBC) presenting as a pararenal mass in a transplant kidney. Cytopathology. 2014;25(4):276-277. https://doi.org/10.1111/cyt.12086.
Gupta M, Venkatesh SK, Kumar A, Pandey R. Fine-needle aspiration cytology of bilateral renal malakoplakia. Diagn Cytopathol. 2004;31(2):116-117.
Srivastava R, Aggarwal S, Arora V. Cutaneous malakoplakia: diagnosed cytologically. Indian J Pathol Microbiol. 2012;55(2):257-258. https://doi.org/10.4103/0377-4929.97900.
Kapasi H, Robertson S, Futter N. Diagnosis of renal malacoplakia by fine needle aspiration cytology: a case report. Acta Cytologica. 1998;42(6):1419-1423.
Lambert C, Gansler T, Mansour KA, Schwartzmann SW, Duffell GM, Gal AA. Pulmonary malakoplakia diagnosed by fine needle aspiration: a case report. Acta Cytologica. 1997;41(6):1833-1838.
Cazzaniga MG, Tommasini-Degna A, Negri R, Pioselli F. Cytologic diagnosis of prostatic malakoplakia. Report of three cases. Acta Cytol. 1987;31(1):48-52.
Pérez-Barrios A, Rodriguez-Peralto JL, Martinez-Gonzalez MA, de Agustin De Agustin P, Lozano F. Malacoplakia of the pelvis. Report of a case with cytologic and ultrastructural findings obtained by fine needle aspiration. Acta Cytol. 1992;36(3):377-380.
Guha S, Liu H. Malakoplakia of the pancreas with simultaneous colon involvement: case report and review of the literature. Case Rep Pathol. 2015;2015:649136.
Saad AJ, Donovan TM, Truong LD. Malakoplakia of the vagina diagnosed by fine-needle aspiration cytology. Diagn Cytopathol. 1993;9(5):559-561.
Chan AC, Lorentz TG, Ma L, Cheung AN, Tse SK. Fine-needle aspiration of cutaneous malakoplakia. Diagn Cytopathol. 1993;9(5):576-580.
Sughayer M, Ali SZ, Erozan YS, Dunsmore N, Hall GS. Pulmonary malacoplakia associated with Rhodococcus equi infection in an AIDS patient. Report of a case with diagnosis by fine needle aspiration. Acta Cytol. 1997;41(2):507-512.
Yousef G, Naghib B. Malakoplakia outside the urinary tract. Arch Pathol Lab Med. 2007;131:297-300.
Kumar P, Hambarsoomina B, Banani S, Vaezzadeh K. Diagnosis of intestinal malakoplakia by fine needle aspiration cytology. Acta Cytol. 1987;31(1):53-56.
Rosai J, Ackerman LV, Rosai J. Rosai and Ackerman's Surgical Pathology. Edinburgh, UK: Mosby; 2011.
Guerra F, Rocher A, Angeleri A, Juarez M, Coliva G, Palaoro L. Von Hansemann cells from fresh urine sediment samples in the diagnosis of malakoplakia. J Cytol. 2019;36(3):165-168.
August C, Holzhausen HJ, Schroder S. Renal parenchymal malakoplakia: ultrastructural findings in different stages of morphogenesis. Ultrastruct Pathol. 1994;18:483-491.
Bates AW, Fegan AW, Baithun SI. Xanthogranulomatous cystitis associated with malignant neoplasms of the bladder. Histopathology. 1998;33:212-215.
Qualman SJ, Gupta PK, Mendelsohn G. Intracellular Escherichia coli in urinary malakoplakia: a reservoir of infection and its therapeutic implications. Am J Clin Pathol. 1984;81:35-42.
Streem SB. Genitourinary malakoplakia in renal transplants recipients: pathogenic, prognostic, and therapeutic considerations. J Urol. 1984;132:10-12.
Archer SR, Abramowsky C, Kobrynski L, et al. Malakoplakia and primary immunodeficiency. J Pediatr. 2014;165(5):1053-1056.
Niknejad N, Nili F, Shirkhoda M. Malakoplakia in association with adenocarcinoma of sigmoid colon: a case report. Iran J Pathol. 2019;14(3):258-260.
Medlicott S, Magi-Galluzzi C, Jimenez R, Trpkov K. Malakoplakia associated with prostatic adenocarcinoma: report of 4 cases and literature review. Ann Diagn Pathol. 2016;22:33-37.
Vijayan M, Koshy P, Parthasarathy R, Mathew M, Abraham G. An unusual association of renal cell carcinoma and renal malakoplakia with focal segmental glomerulosclerosis in an elderly patient. Indian J Nephrol. 2018;28(6):485-487.

Auteurs

Linh Ho (L)

Department of Pathology, University of Colorado, Aurora, Colorado.

Sanjana Mehrotra (S)

Department of Pathology, University of Colorado, Aurora, Colorado.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH