Further characterization of distinct high-affinity binding sites for dinotefuran in the abdominal nerve cord of the American cockroach Periplaneta americana (Blattodea).
Binding site
Dinotefuran
Neonicotinoids
Nicotinic acetylcholine receptor
Periplaneta americana
Two-site model
Journal
Pesticide biochemistry and physiology
ISSN: 1095-9939
Titre abrégé: Pestic Biochem Physiol
Pays: United States
ID NLM: 1301573
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
received:
11
10
2019
revised:
27
02
2020
accepted:
28
02
2020
entrez:
4
5
2020
pubmed:
4
5
2020
medline:
6
5
2020
Statut:
ppublish
Résumé
Dinotefuran (DTF) is a systemic neonicotinoid insecticide characterized by a tetrahydrofuran ring. In the present study, we examined the characteristics of DTF binding to native nicotinic acetylcholine receptors (nAChRs) expressed in the American cockroach Periplaneta americana using radioligand-binding methods. The Scatchard analysis, using [
Identifiants
pubmed: 32359545
pii: S0048-3575(20)30049-3
doi: 10.1016/j.pestbp.2020.104554
pii:
doi:
Substances chimiques
Guanidines
0
Insecticides
0
Neonicotinoids
0
Nitro Compounds
0
Receptors, Nicotinic
0
dinotefuran
1W509710WF
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
104554Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.