Brain function and clinical characterization in the Boston adolescent neuroimaging of depression and anxiety study.


Journal

NeuroImage. Clinical
ISSN: 2213-1582
Titre abrégé: Neuroimage Clin
Pays: Netherlands
ID NLM: 101597070

Informations de publication

Date de publication:
2020
Historique:
received: 13 11 2019
revised: 09 03 2020
accepted: 10 03 2020
pubmed: 4 5 2020
medline: 9 3 2021
entrez: 4 5 2020
Statut: ppublish

Résumé

We present a Human Connectome Project study tailored toward adolescent anxiety and depression. This study is one of the first studies of the Connectomes Related to Human Diseases initiative and is collecting structural, functional, and diffusion-weighted brain imaging data from up to 225 adolescents (ages 14-17 years), 150 of whom are expected to have a current diagnosis of an anxiety and/or depressive disorder. Comprehensive clinical and neuropsychological evaluations and longitudinal clinical data are also being collected. This article provides an overview of task functional magnetic resonance imaging (fMRI) protocols and preliminary findings (N = 140), as well as clinical and neuropsychological characterization of adolescents. Data collection is ongoing for an additional 85 adolescents, most of whom are expected to have a diagnosis of an anxiety and/or depressive disorder. Data from the first 140 adolescents are projected for public release through the National Institutes of Health Data Archive (NDA) with the timing of this manuscript. All other data will be made publicly-available through the NDA at regularly scheduled intervals. This article is intended to serve as an introduction to this project as well as a reference for those seeking to clinical, neurocognitive, and task fMRI data from this public resource.

Identifiants

pubmed: 32361633
pii: S2213-1582(20)30077-2
doi: 10.1016/j.nicl.2020.102240
pmc: PMC7199015
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

102240

Subventions

Organisme : NIMH NIH HHS
ID : R01 MH101521
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB021265
Pays : United States
Organisme : NCRR NIH HHS
ID : S10 RR019307
Pays : United States
Organisme : NCCIH NIH HHS
ID : R01 AT007257
Pays : United States
Organisme : NIMH NIH HHS
ID : R56 MH121426
Pays : United States
Organisme : NIMH NIH HHS
ID : U01 MH108168
Pays : United States
Organisme : NIMH NIH HHS
ID : R37 MH068376
Pays : United States
Organisme : NIBIB NIH HHS
ID : P41 EB019936
Pays : United States
Organisme : NIBIB NIH HHS
ID : U01 EB026996
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB020740
Pays : United States
Organisme : NIMH NIH HHS
ID : F32 MH114525
Pays : United States
Organisme : NCRR NIH HHS
ID : S10 RR023043
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH099021
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH096987
Pays : United States
Organisme : NCRR NIH HHS
ID : S10 RR023401
Pays : United States

Informations de copyright

Copyright © 2020. Published by Elsevier Inc.

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Auteurs

N A Hubbard (NA)

Massachusetts Institute of Technology, Cambridge, MA, United States; University of Nebraska-Lincoln, Lincoln, NE, United States.

V Siless (V)

Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States.

I R Frosch (IR)

Massachusetts Institute of Technology, Cambridge, MA, United States.

M Goncalves (M)

Massachusetts Institute of Technology, Cambridge, MA, United States.

N Lo (N)

Massachusetts Institute of Technology, Cambridge, MA, United States.

J Wang (J)

Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States.

C C C Bauer (CCC)

Massachusetts Institute of Technology, Cambridge, MA, United States.

K Conroy (K)

Boston University, Boston, MA, United States.

E Cosby (E)

Harvard Medical School, Boston, MA, United States; McLean Hospital, Belmont, MA, United States.

A Hay (A)

Boston University, Boston, MA, United States.

R Jones (R)

Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States.

M Pinaire (M)

Boston University, Boston, MA, United States.

F Vaz De Souza (F)

Harvard Medical School, Boston, MA, United States; Massachusetts General Hospital, Boston, MA, United States.

G Vergara (G)

Harvard Medical School, Boston, MA, United States; McLean Hospital, Belmont, MA, United States.

S Ghosh (S)

Massachusetts Institute of Technology, Cambridge, MA, United States; Harvard Medical School, Boston, MA, United States.

A Henin (A)

Harvard Medical School, Boston, MA, United States; Massachusetts General Hospital, Boston, MA, United States.

D R Hirshfeld-Becker (DR)

Harvard Medical School, Boston, MA, United States; Massachusetts General Hospital, Boston, MA, United States.

S G Hofmann (SG)

Boston University, Boston, MA, United States.

I M Rosso (IM)

Harvard Medical School, Boston, MA, United States; McLean Hospital, Belmont, MA, United States.

R P Auerbach (RP)

Columbia University, New York, NY, United States.

D A Pizzagalli (DA)

Harvard Medical School, Boston, MA, United States; McLean Hospital, Belmont, MA, United States.

A Yendiki (A)

Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States.

J D E Gabrieli (JDE)

Massachusetts Institute of Technology, Cambridge, MA, United States.

S Whitfield-Gabrieli (S)

Massachusetts Institute of Technology, Cambridge, MA, United States; Northeastern University, Boston, MA, United States. Electronic address: s.whitfield-gabrieli@northeastern.edu.

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Classifications MeSH