Selective N7 Alkylation of 7-Azaindazoles.
Journal
The Journal of organic chemistry
ISSN: 1520-6904
Titre abrégé: J Org Chem
Pays: United States
ID NLM: 2985193R
Informations de publication
Date de publication:
05 06 2020
05 06 2020
Historique:
pubmed:
5
5
2020
medline:
5
5
2020
entrez:
5
5
2020
Statut:
ppublish
Résumé
A general and mild procedure for alkylation of 7-azaindazoles at the N7 position using alkyl halides in butanone is reported, which requires no additives such as acids or bases. The scope of the reaction regarding substituents on 7-azaindazoles and the alkyl electrophiles is presented.
Identifiants
pubmed: 32362114
doi: 10.1021/acs.joc.0c00722
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM