Nails: The Window to the Nose? Update on Yellow Nail Syndrome.
arrested nail growth
lichen planus
respiratory disease
yellow nail syndrome
Journal
Dermatology practical & conceptual
ISSN: 2160-9381
Titre abrégé: Dermatol Pract Concept
Pays: Austria
ID NLM: 101585990
Informations de publication
Date de publication:
2020
2020
Historique:
accepted:
06
12
2019
entrez:
5
5
2020
pubmed:
5
5
2020
medline:
5
5
2020
Statut:
epublish
Résumé
Yellow nail syndrome is a rare condition characterized by typical nail alterations and variable presence of lymphedema and respiratory disease. The pathogenesis is still obscure, with most of the literature deriving from case reports and few investigations. The most reported respiratory conditions associated with yellow nail syndrome are pleural effusion and bronchiectasis, whereas association with rhinosinusitis is rarer. To describe a case of yellow nail syndrome and to provide a literature review regarding this disorder, discussing pathogenetic hypothesis, associated conditions, and therapeutic options. A 49-year-old man presented with arrested growth and alterations of his nails, without any history of previous trauma or inflammation but with a severe nasal septum deviation and a history of chronic rhinosinusitis. A diagnosis of yellow nail syndrome was made. Six months after undergoing rhinoseptoplasty and treatment with oral vitamin E, the patient's nails were cured. This case emphasizes the role of the dermatologist in detecting systemic conditions. The correct diagnosis led to complete resolution of both nail alterations and associated respiratory disorders.
Sections du résumé
BACKGROUND
BACKGROUND
Yellow nail syndrome is a rare condition characterized by typical nail alterations and variable presence of lymphedema and respiratory disease. The pathogenesis is still obscure, with most of the literature deriving from case reports and few investigations. The most reported respiratory conditions associated with yellow nail syndrome are pleural effusion and bronchiectasis, whereas association with rhinosinusitis is rarer.
OBJECTIVES
OBJECTIVE
To describe a case of yellow nail syndrome and to provide a literature review regarding this disorder, discussing pathogenetic hypothesis, associated conditions, and therapeutic options.
PATIENTS/METHODS
METHODS
A 49-year-old man presented with arrested growth and alterations of his nails, without any history of previous trauma or inflammation but with a severe nasal septum deviation and a history of chronic rhinosinusitis. A diagnosis of yellow nail syndrome was made.
RESULTS
RESULTS
Six months after undergoing rhinoseptoplasty and treatment with oral vitamin E, the patient's nails were cured.
CONCLUSIONS
CONCLUSIONS
This case emphasizes the role of the dermatologist in detecting systemic conditions. The correct diagnosis led to complete resolution of both nail alterations and associated respiratory disorders.
Identifiants
pubmed: 32363094
doi: 10.5826/dpc.1002a31
pii: dp1002a31
pmc: PMC7190560
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e2020031Informations de copyright
©2020 Vollono et al.
Déclaration de conflit d'intérêts
Competing interests: The authors have no conflicts of interest to disclose.
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