Investigation of interaction phenomena between lower urinary tract and artificial urinary sphincter in consideration of urethral tissues degeneration.


Journal

Biomechanics and modeling in mechanobiology
ISSN: 1617-7940
Titre abrégé: Biomech Model Mechanobiol
Pays: Germany
ID NLM: 101135325

Informations de publication

Date de publication:
Dec 2020
Historique:
received: 20 12 2019
accepted: 02 04 2020
pubmed: 5 5 2020
medline: 24 8 2021
entrez: 5 5 2020
Statut: ppublish

Résumé

Lower urinary tract dysfunction pertains to symptoms related to the lower urinary tract (LUT), with consequent incontinence. Artificial urinary sphincters (AUS) are adopted to obtain continence conditions, mainly in male subjects, via urethral occlusion by applying pressure load, mostly operating on the basis of an empirical approach. Considering the frequent access of elderly patients to this surgical practice, tissue degradation related to aging phenomena must be investigated. Computational models of the LUT structures and the AUS systems have been designed to evaluate tissues mechanical stimulation and degenerative phenomena for reciprocal interaction. Virtual solid models of the LUT have been developed starting from biomedical images, as histological/morphometrical data. Segmentation procedures have been exploited to provide the three-dimensional reconstruction, and subsequent discretization techniques led to the finite element model. Contemporarily, a finite element model of a typical AUS device was developed. Numerical analyses have been performed to analyze interaction phenomena between AUS and LUT. Different conditions were investigated, modifying both loading conditions, as intraluminal pressure and AUS action, and urethral tissues properties. Particular attention was devoted to tissues parameters, aiming to evaluate the influence of tissues degeneration because of aging and/or pathologies.

Identifiants

pubmed: 32363532
doi: 10.1007/s10237-020-01326-3
pii: 10.1007/s10237-020-01326-3
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2099-2109

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Auteurs

Arturo Nicola Natali (AN)

Department of Industrial Engineering, University of Padova, Via Venezia 1, 35131, Padua, Italy.
Centre for Mechanics of Biological Materials, University of Padova, Padua, Italy.

Emanuele Luigi Carniel (EL)

Department of Industrial Engineering, University of Padova, Via Venezia 1, 35131, Padua, Italy. emanueleluigi.carniel@unipd.it.
Centre for Mechanics of Biological Materials, University of Padova, Padua, Italy. emanueleluigi.carniel@unipd.it.

Chiara Giulia Fontanella (CG)

Department of Industrial Engineering, University of Padova, Via Venezia 1, 35131, Padua, Italy.
Centre for Mechanics of Biological Materials, University of Padova, Padua, Italy.

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