Genome-wide association studies for the number of teats and teat asymmetry patterns in Large White pigs.
Sus scrofa
TOX3
VRTN
GWAS
single nucleotide polymorphism
Journal
Animal genetics
ISSN: 1365-2052
Titre abrégé: Anim Genet
Pays: England
ID NLM: 8605704
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
accepted:
13
04
2020
pubmed:
5
5
2020
medline:
21
11
2020
entrez:
5
5
2020
Statut:
ppublish
Résumé
The number of teats is a morphological trait that influences the mothering ability of the sows and thus their reproduction performances. In this study, we carried out GWASs for the total number of teats and other 12 related parameters in 821 Italian Large White heavy pigs. All pigs were genotyped with the Illumina PorcineSNP60 BeadChip array. For four investigated parameters (total number of teats, the number of teats of the left line, the number of teats of the right line and the maximum number of teats comparing the two sides), significant markers were identified on SSC7, in the region of the vertnin (VRTN) gene. Significant markers for the numbers of posterior teats and the absolute difference between anterior and posterior teat numbers were consistently identified on SSC6. The most significant SNP for these parameters was an intron variant in the TOX high mobility group box family member 3 (TOX3) gene. For the other four parameters (absolute difference between the two sides; anterior teats; the ratio between the posterior and the anterior number of teats; and the absence or the presence of extra teats) only suggestively significant markers were identified on several other chromosomes. This study further supported the role of the VRTN gene region in affecting the recorded variability of the number of teats in the Italian Large White pig population and identified a genomic region potentially affecting the biological mechanisms controlling the developmental programme of morphological features in pigs.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
595-600Subventions
Organisme : Italian MiPAAF Innovagen Project
Organisme : Italian MIUR PRIN2017 PigPhenomics Project
Organisme : University of Bologna RFO 2018-2019 Programmes
Organisme : European Agricultural Fund for Rural Development of the European Union
Organisme : Italian Ministry of Agriculture, Food, Forestry and Tourism - MiPAAFT
Informations de copyright
© 2020 Stichting International Foundation for Animal Genetics.
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