TGF-β signaling regulates
SMAD3
SPOP
TGF-β signaling
prostate cancer
stemness
Journal
Aging
ISSN: 1945-4589
Titre abrégé: Aging (Albany NY)
Pays: United States
ID NLM: 101508617
Informations de publication
Date de publication:
01 05 2020
01 05 2020
Historique:
received:
24
10
2019
accepted:
25
02
2020
pubmed:
5
5
2020
medline:
26
2
2021
entrez:
5
5
2020
Statut:
ppublish
Résumé
SPOP, a substrate binding adaptor of E3 ubiquitin ligase Cullin3, is frequently mutated in human prostate cancer (PCa). However, whether and how SPOP is regulated at transcriptional level in PCa remain unclear. Here, we report that
Identifiants
pubmed: 32364525
pii: 103085
doi: 10.18632/aging.103085
pmc: PMC7244043
doi:
Substances chimiques
Nuclear Proteins
0
RNA, Neoplasm
0
Repressor Proteins
0
SPOP protein, human
0
Transforming Growth Factor beta
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
7747-7760Références
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