Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function.

Animals Biomedical Research / standards Cardiovascular Diseases / diagnostic imaging Consensus Diastole Disease Models, Animal Echocardiography / standards Mice Rats Systole Ventricular Function, Left
Animal models Diastolic function Echocardiography Standardization Systolic function

Journal

Cardiovascular research
ISSN: 1755-3245
Titre abrégé: Cardiovasc Res
Pays: England
ID NLM: 0077427

Informations de publication

Date de publication:
01 01 2021
Historique:
received: 24 09 2019
revised: 28 01 2020
accepted: 24 04 2020
pubmed: 5 5 2020
medline: 7 10 2021
entrez: 5 5 2020
Statut: ppublish

Résumé

Echocardiography is a reliable and reproducible method to assess non-invasively cardiac function in clinical and experimental research. Significant progress in the development of echocardiographic equipment and transducers has led to the successful translation of this methodology from humans to rodents, allowing for the scoring of disease severity and progression, testing of new drugs, and monitoring cardiac function in genetically modified or pharmacologically treated animals. However, as yet, there is no standardization in the procedure to acquire echocardiographic measurements in small animals. This position paper focuses on the appropriate acquisition and analysis of echocardiographic parameters in adult mice and rats, and provides reference values, representative images, and videos for the accurate and reproducible quantification of left ventricular function in healthy and pathological conditions.

Identifiants

DOI: 10.1093/cvr/cvaa110 PMID: 32365197
pubmed: 32365197
pii: 5828935
doi: 10.1093/cvr/cvaa110
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review Video-Audio Media

Langues

eng

Sous-ensembles de citation

IM

Pagination

43-59

Subventions

Organisme : British Heart Foundation
ID : CH/16/3/32406
Pays : United Kingdom
Organisme : British Heart Foundation
ID : RG/16/14/32397
Pays : United Kingdom

Informations de copyright

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: journals.permissions@oup.com.

Auteurs

Serena Zacchigna (S)

Department of Medicine, Surgery and Health Sciences and Cardiovascular Department, Centre for Translational Cardiology, Azienda Sanitaria Universitaria Giuliano Isontina, strada di Fiume 447, 34149 Trieste (TS), Italy.
International Center for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.

Alessia Paldino (A)

Department of Medicine, Surgery and Health Sciences and Cardiovascular Department, Centre for Translational Cardiology, Azienda Sanitaria Universitaria Giuliano Isontina, strada di Fiume 447, 34149 Trieste (TS), Italy.

Inês Falcão-Pires (I)

Cardiovascular Research and Development Center, Faculty of Medicine, University of Porto, Porto, Portugal.

Evangelos P Daskalopoulos (EP)

Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain (UCLouvain), Belgium, Brussels.

Matteo Dal Ferro (M)

Department of Medicine, Surgery and Health Sciences and Cardiovascular Department, Centre for Translational Cardiology, Azienda Sanitaria Universitaria Giuliano Isontina, strada di Fiume 447, 34149 Trieste (TS), Italy.

Simone Vodret (S)

International Center for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.

Pierluigi Lesizza (P)

Department of Medicine, Surgery and Health Sciences and Cardiovascular Department, Centre for Translational Cardiology, Azienda Sanitaria Universitaria Giuliano Isontina, strada di Fiume 447, 34149 Trieste (TS), Italy.

Antonio Cannatà (A)

Department of Medicine, Surgery and Health Sciences and Cardiovascular Department, Centre for Translational Cardiology, Azienda Sanitaria Universitaria Giuliano Isontina, strada di Fiume 447, 34149 Trieste (TS), Italy.

Daniela Miranda-Silva (D)

Cardiovascular Research and Development Center, Faculty of Medicine, University of Porto, Porto, Portugal.

André P Lourenço (AP)

Cardiovascular Research and Development Center, Faculty of Medicine, University of Porto, Porto, Portugal.

Bruno Pinamonti (B)

Department of Medicine, Surgery and Health Sciences and Cardiovascular Department, Centre for Translational Cardiology, Azienda Sanitaria Universitaria Giuliano Isontina, strada di Fiume 447, 34149 Trieste (TS), Italy.

Gianfranco Sinagra (G)

Department of Medicine, Surgery and Health Sciences and Cardiovascular Department, Centre for Translational Cardiology, Azienda Sanitaria Universitaria Giuliano Isontina, strada di Fiume 447, 34149 Trieste (TS), Italy.

Florian Weinberger (F)

Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Germany.

Thomas Eschenhagen (T)

Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Germany.

Lucie Carrier (L)

Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Germany.

Izhak Kehat (I)

Department of Physiology, Biophysics and System Biology, The Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.

Carlo G Tocchetti (CG)

Department of Translational Medical Sciences, Federico II University, Naples, Italy.
Interdepartmental Center of Clinical and Translational Research (CIRCET), Federico II University, Naples, Italy.

Michele Russo (M)

Department of Translational Medical Sciences, Federico II University, Naples, Italy.
Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.

Alessandra Ghigo (A)

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.

James Cimino (J)

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.

Emilio Hirsch (E)

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.

Dana Dawson (D)

School of Medicine and Dentistry, University of Aberdeen, Aberdeen, UK.

Michele Ciccarelli (M)

University of Salerno, Salerno, Italy.

Marco Oliveti (M)

University of Salerno, Salerno, Italy.

Wolfgang A Linke (WA)

Institute of Physiology 2, University of Muenster, Muenster, Germany.

Ilona Cuijpers (I)

Maastricht University Medical Centre, Maastricht University, Maastricht, The Netherlands.
Center of Molecular and Vascular Biology (CMVB), KU Leuven, Leuven, Belgium.

Stephane Heymans (S)

Maastricht University Medical Centre, Maastricht University, Maastricht, The Netherlands.
Center of Molecular and Vascular Biology (CMVB), KU Leuven, Leuven, Belgium.

Nazha Hamdani (N)

Department of Molecular and Experimental Cardiology, Division Cardiology, St. Josef-Hospital, Ruhr University Bochum, Bochum, Germany.
Institute of Physiology, Ruhr University Bochum, Bochum, Germany.

Martine de Boer (M)

Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Dirk J Duncker (DJ)

Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Diederik Kuster (D)

Department of Physiology, Amsterdam UMC, Vrije Universiteit, Amsterdam Cardiovascular Sciences Institute, Amsterdam, The Netherlands.

Jolanda van der Velden (J)

Department of Physiology, Amsterdam UMC, Vrije Universiteit, Amsterdam Cardiovascular Sciences Institute, Amsterdam, The Netherlands.

Christophe Beauloye (C)

Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain (UCLouvain), Belgium, Brussels.
Division of Cardiology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.

Luc Bertrand (L)

Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain (UCLouvain), Belgium, Brussels.

Manuel Mayr (M)

King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK.

Mauro Giacca (M)

Department of Medicine, Surgery and Health Sciences and Cardiovascular Department, Centre for Translational Cardiology, Azienda Sanitaria Universitaria Giuliano Isontina, strada di Fiume 447, 34149 Trieste (TS), Italy.
International Center for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK.

Florian Leuschner (F)

Institute of Experimental Cardiology, Department of Cardiology, Angiology & Pulmology, Heidelberg University Hospital, Heidelberg, Germany.
DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany.

Johannes Backs (J)

Institute of Experimental Cardiology, Department of Cardiology, Angiology & Pulmology, Heidelberg University Hospital, Heidelberg, Germany.
DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, Heidelberg, Germany.

Thomas Thum (T)

Institute for Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Hannover, Germany.
REBIRTH Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Towards standardization of echocardiography...
questionsmedicales.fr › Disciplines des sciences naturelles › Science › Recherche › Recherche biomédicale › Towards standardization of echocardiography...
questionsmedicales.fr › Maladies cardiovasculaires › Towards standardization of echocardiography...
questionsmedicales.fr › Phénomènes psychologiques › Processus mentaux › Pensée (activité mentale) › Prise de décision › Consensus › Towards standardization of echocardiography...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Contraction musculaire › Contraction myocardique › Diastole › Towards standardization of echocardiography...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Towards standardization of echocardiography...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic cardiovasculaire › Tests de la fonction cardiaque › Échocardiographie › Towards standardization of echocardiography...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Towards standardization of echocardiography...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Towards standardization of echocardiography...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Contraction musculaire › Contraction myocardique › Systole › Towards standardization of echocardiography...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Fonction ventriculaire › Fonction ventriculaire gauche › Towards standardization of echocardiography...