Weight cycling is associated with adverse cardiometabolic markers in a cross-sectional representative US sample.
Adult
Biomarkers
/ blood
Blood Pressure
/ physiology
Body Composition
/ physiology
Cardiovascular Diseases
/ blood
Cholesterol, HDL
/ blood
Cross-Sectional Studies
Female
Humans
Insulin
/ blood
Insulin Resistance
/ physiology
Male
Metabolic Syndrome
/ blood
Middle Aged
Nutrition Surveys
Risk Factors
Sex Factors
Weight Gain
/ physiology
Weight Loss
/ physiology
Epidemiology
Obesity
cardiometabolic
weight cycling
Journal
Journal of epidemiology and community health
ISSN: 1470-2738
Titre abrégé: J Epidemiol Community Health
Pays: England
ID NLM: 7909766
Informations de publication
Date de publication:
08 2020
08 2020
Historique:
received:
25
10
2019
revised:
27
02
2020
accepted:
14
04
2020
pubmed:
6
5
2020
medline:
30
12
2020
entrez:
6
5
2020
Statut:
ppublish
Résumé
Whether weight cycling (repeated weight loss and regain) is associated with cardiometabolic health is unclear. Study objective was to examine whether weight cycling since young adulthood (ie, 25 years of age) was associated with cardiometabolic markers. Data from a nationally representative cross-sectional US sample (National Health and Nutrition Examination Survey, 1999-2014) were used. Weight history was based on self-reported weight at age 25, 10 years prior and 1 year prior to the survey (n=4190, 51% male). Using current self-reported weight as the anchor, participants were classified as (1) Compared with females with Weight cycling is adversely associated with cardiometabolic markers but associations differ by sex and weight status. While weight cycling is consistently associated with worse cardiometabolic markers among females, results are mixed among males. Weight cycling is associated with worse lipid measures for normal weight persons, and marginally worse insulin sensitivity for those with overweight/obesity.
Sections du résumé
BACKGROUND
Whether weight cycling (repeated weight loss and regain) is associated with cardiometabolic health is unclear. Study objective was to examine whether weight cycling since young adulthood (ie, 25 years of age) was associated with cardiometabolic markers.
METHODS
Data from a nationally representative cross-sectional US sample (National Health and Nutrition Examination Survey, 1999-2014) were used. Weight history was based on self-reported weight at age 25, 10 years prior and 1 year prior to the survey (n=4190, 51% male). Using current self-reported weight as the anchor, participants were classified as (1)
RESULTS
Compared with females with
CONCLUSION
Weight cycling is adversely associated with cardiometabolic markers but associations differ by sex and weight status. While weight cycling is consistently associated with worse cardiometabolic markers among females, results are mixed among males. Weight cycling is associated with worse lipid measures for normal weight persons, and marginally worse insulin sensitivity for those with overweight/obesity.
Identifiants
pubmed: 32366587
pii: jech-2019-213419
doi: 10.1136/jech-2019-213419
pmc: PMC7320743
doi:
Substances chimiques
Biomarkers
0
Cholesterol, HDL
0
Insulin
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
662-667Informations de copyright
© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
Can J Cardiol. 2017 Mar;33(3):343-349
pubmed: 28034582
Am J Prev Med. 2010 Dec;39(6):546-54
pubmed: 21084075
Am J Epidemiol. 2005 Jun 15;161(12):1133-43
pubmed: 15937022
Clin Chem. 1972 Jun;18(6):499-502
pubmed: 4337382
Obes Res Clin Pract. 2017 Mar - Apr;11(2):131-139
pubmed: 27773644
Metabolism. 2013 Jan;62(1):127-36
pubmed: 22898251
Am J Epidemiol. 2010 Mar 1;171(5):550-6
pubmed: 20110286
Curr Opin Lipidol. 2011 Feb;22(1):43-8
pubmed: 21233620
Arch Intern Med. 1995 Jul 10;155(13):1416-22
pubmed: 7794091
Lancet Public Health. 2017 May 19;2(6):e277-e285
pubmed: 28626830
Obesity (Silver Spring). 2018 Nov;26(11):1733-1739
pubmed: 30358151
Diabetologia. 1985 Jul;28(7):412-9
pubmed: 3899825
Eur J Epidemiol. 2010 May;25(5):333-9
pubmed: 20352298
Int J Obes (Lond). 2008 Feb;32(2):315-21
pubmed: 17968381
Biores Open Access. 2018 Jun 01;7(1):90-100
pubmed: 29892497
Int J Obes Relat Metab Disord. 1999 Dec;23(12):1314-9
pubmed: 10643690
Am J Prev Med. 2007 Jul;33(1):34-40
pubmed: 17572309
Diabetes Care. 2016 Aug;39(8):1345-55
pubmed: 27271190
JAMA Netw Open. 2019 Mar 1;2(3):e190731
pubmed: 30874785
J Hypertens. 2012 May;30(5):1042-5
pubmed: 22495140
Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):572-7
pubmed: 26729881
Int J Obes Relat Metab Disord. 2004 Jan;28(1):65-71
pubmed: 14647176
J Diabetes Investig. 2017 Jul;8(4):501-509
pubmed: 28083921
Obes Res. 2005 Feb;13(2):333-41
pubmed: 15800292
Diabetes Care. 2012 Feb;35(2):342-9
pubmed: 22190676
Obes Rev. 2014 Nov;15(11):870-81
pubmed: 25263568
Obes Res. 2004 Feb;12(2):267-74
pubmed: 14981219
J Clin Endocrinol Metab. 2000 Jul;85(7):2402-10
pubmed: 10902785
Nutrients. 2018 Nov 10;10(11):
pubmed: 30423846
Am J Epidemiol. 2010 Jul 15;172(2):180-9
pubmed: 20519263