Ultrasonographic assessment of skeletal muscle mass and diaphragm function in patients with chronic obstructive pulmonary disease: A case-control study.

Chronic obstructive pulmonary disease diaphragm excursion and thickness rectus femoris cross-sectional area ultrasound zone of apposition

Journal

Lung India : official organ of Indian Chest Society
ISSN: 0970-2113
Titre abrégé: Lung India
Pays: India
ID NLM: 8405380

Informations de publication

Date de publication:
Historique:
entrez: 6 5 2020
pubmed: 6 5 2020
medline: 6 5 2020
Statut: ppublish

Résumé

Although muscle dysfunction is a major contributor to morbidity in chronic obstructive pulmonary disease (COPD), assessment of skeletal muscle, and diaphragm function is not routinely performed in COPD patients. (1) The aim is to assess muscle dysfunction in COPD by measuring the zone of apposition of diaphragm, diaphragm excursion, thickness of diaphragm, and rectus femoris cross-sectional area (RFCSA) with ultrasonography.(2) To correlate the above assessments with spirometric parameters; notably forced expiratory volume in 1 s (FEV Twenty-four consecutive stable COPD patients and 18 controls were included after obtaining written informed consent. Demographic and clinical data, spirometric values, 6-min walk distance, and sonographic parameters mentioned above were compiled for the analysis. All included participants were male with a mean age of 62.5 ± 8.4 years. The mean FEV Ultrasonographic assessment of the diaphragm and rectus femoris can be used as markers to assess skeletal muscle dysfunction in COPD as diaphragmatic function and RFCSA were lower in COPD patients.

Sections du résumé

BACKGROUND BACKGROUND
Although muscle dysfunction is a major contributor to morbidity in chronic obstructive pulmonary disease (COPD), assessment of skeletal muscle, and diaphragm function is not routinely performed in COPD patients.
OBJECTIVES OBJECTIVE
(1) The aim is to assess muscle dysfunction in COPD by measuring the zone of apposition of diaphragm, diaphragm excursion, thickness of diaphragm, and rectus femoris cross-sectional area (RFCSA) with ultrasonography.(2) To correlate the above assessments with spirometric parameters; notably forced expiratory volume in 1 s (FEV
METHODS METHODS
Twenty-four consecutive stable COPD patients and 18 controls were included after obtaining written informed consent. Demographic and clinical data, spirometric values, 6-min walk distance, and sonographic parameters mentioned above were compiled for the analysis.
RESULTS RESULTS
All included participants were male with a mean age of 62.5 ± 8.4 years. The mean FEV
CONCLUSION CONCLUSIONS
Ultrasonographic assessment of the diaphragm and rectus femoris can be used as markers to assess skeletal muscle dysfunction in COPD as diaphragmatic function and RFCSA were lower in COPD patients.

Identifiants

pubmed: 32367843
pii: LungIndia_2020_37_3_220_283731
doi: 10.4103/lungindia.lungindia_103_19
pmc: PMC7353944
doi:

Types de publication

Journal Article

Langues

eng

Pagination

220-226

Déclaration de conflit d'intérêts

None

Références

Int J Chron Obstruct Pulmon Dis. 2009;4:137-48
pubmed: 19436692
Intensive Care Med. 2013 May;39(5):801-10
pubmed: 23344830
Respir Med. 2007 Oct;101(10):2113-8
pubmed: 17644365
Am J Respir Crit Care Med. 2002 Dec 1;166(11):1461-9
pubmed: 12406839
J Appl Physiol (1985). 2009 Aug;107(2):621-9
pubmed: 19390004
Thorax. 1995 Nov;50(11):1157-61
pubmed: 8553271
Chron Respir Dis. 2018 May;15(2):182-219
pubmed: 28580854
Phys Ther. 2008 Feb;88(2):219-30
pubmed: 18056754
Thorax. 2012 Dec;67(12):1102-9
pubmed: 22561528
Int J Chron Obstruct Pulmon Dis. 2015 Sep 11;10:1925-30
pubmed: 26392767
J Appl Physiol (1985). 1996 Jul;81(1):238-45
pubmed: 8828670
J Appl Physiol (1985). 2016 Aug 1;121(2):391-400
pubmed: 27283911
Am J Respir Crit Care Med. 2002 Sep 15;166(6):809-13
pubmed: 12231489
Respir Physiol Neurobiol. 2015 May;210:23-9
pubmed: 25602916
Respiration. 2014;87(5):364-71
pubmed: 24732295
J Glob Health. 2015 Dec;5(2):020415
pubmed: 26755942
Respir Med. 2006 Oct;100(10):1800-6
pubmed: 16545558
Respir Res. 2012 Dec 28;13:119
pubmed: 23273255
Eur Respir J. 2013 Sep;42(3):616-25
pubmed: 23349449
J Appl Physiol (1985). 2001 Jun;90(6):2070-4
pubmed: 11356767
Chest. 2009 Feb;135(2):391-400
pubmed: 19017880
Am J Respir Crit Care Med. 1999 Apr;159(4 Pt 2):S1-40
pubmed: 10194189
Thorax. 2009 May;64(5):418-23
pubmed: 19158125
Crit Care Med. 2011 Dec;39(12):2627-30
pubmed: 21705883
Chest. 2014 Sep;146(3):680-685
pubmed: 24700122
Respir Care. 2017 Dec;62(12):1565-1570
pubmed: 28874613

Auteurs

Priya Ramachandran (P)

Department of Pulmonary and Sleep Medicine, St. John's Medical College, Bengaluru, Karnataka, India.

Uma Devaraj (U)

Department of Pulmonary and Sleep Medicine, St. John's Medical College, Bengaluru, Karnataka, India.

Bhavna Patrick (B)

Department of Pulmonary and Sleep Medicine, St. John's Medical College, Bengaluru, Karnataka, India.

Deepali Saxena (D)

Department of Radiology, St. John's Medical College, Bengaluru, Karnataka, India.

Kavitha Venkatnarayan (K)

Department of Pulmonary Medicine, St. John's Medical College, Bengaluru, Karnataka, India.

Varghese Louis (V)

Department of Pulmonary Medicine, St. John's Medical College, Bengaluru, Karnataka, India.

Uma Maheswari Krishnaswamy (UM)

Department of Pulmonary and Sleep Medicine, St. John's Medical College, Bengaluru, Karnataka, India.

George A D'souza (GA)

Department of Pulmonary and Sleep Medicine, St. John's Medical College, Bengaluru, Karnataka, India.

Classifications MeSH