Cyclodextrin-Modified CeO
Animals
Catalase
/ metabolism
Cell Line
Cell Survival
Cerium
/ chemistry
Combined Modality Therapy
Free Radical Scavengers
/ chemistry
Hydrodynamics
Imiquimod
/ pharmacology
Male
Mice, Inbred BALB C
Nanoparticles
/ chemistry
Particle Size
Photoelectron Spectroscopy
Psoriasis
/ drug therapy
Reactive Oxygen Species
/ metabolism
Skin
/ drug effects
Spectroscopy, Fourier Transform Infrared
Superoxide Dismutase
/ metabolism
Tumor Necrosis Factor-alpha
/ metabolism
beta-Cyclodextrins
/ chemical synthesis
anti-psoriatic
dithranol
drug delivery
mimic-enzyme
reactive oxygen species
ceria nanoparticles
Journal
International journal of nanomedicine
ISSN: 1178-2013
Titre abrégé: Int J Nanomedicine
Pays: New Zealand
ID NLM: 101263847
Informations de publication
Date de publication:
2020
2020
Historique:
received:
21
01
2020
accepted:
24
03
2020
entrez:
6
5
2020
pubmed:
6
5
2020
medline:
3
7
2020
Statut:
epublish
Résumé
Reactive oxygen species (ROS)-induced oxidative stress plays a key role in the pathogenesis and progression of psoriasis by causing inflammation. Antioxidative strategies eradicating ROS may serve as effective and easy treatment options for psoriasis, while nanozymes with intrinsic antioxidant enzyme-like activity have not been explored for psoriasis treatment. The aim of this study is to fabricate β-cyclodextrins (β-CDs)-modified ceria nanoparticles (β-CDs/CeO The β-CDs/CeO The average particle size of the blank β-CDs/CeO This study may pave the way for the application of nanozyme β-CDs/CeO
Identifiants
pubmed: 32368038
doi: 10.2147/IJN.S246783
pii: 246783
pmc: PMC7170634
doi:
Substances chimiques
Free Radical Scavengers
0
Reactive Oxygen Species
0
Tumor Necrosis Factor-alpha
0
beta-Cyclodextrins
0
Cerium
30K4522N6T
ceric oxide
619G5K328Y
Catalase
EC 1.11.1.6
Superoxide Dismutase
EC 1.15.1.1
Imiquimod
P1QW714R7M
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2515-2527Informations de copyright
© 2020 Wu et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
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