Editorial Commentary: Orthobiologics-The Evolution From Symptom to Structural Modification in the Treatment of Articular Cartilage Defects.
Journal
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
ISSN: 1526-3231
Titre abrégé: Arthroscopy
Pays: United States
ID NLM: 8506498
Informations de publication
Date de publication:
05 2020
05 2020
Historique:
received:
02
03
2020
accepted:
03
03
2020
entrez:
7
5
2020
pubmed:
7
5
2020
medline:
17
6
2020
Statut:
ppublish
Résumé
The race is on to identify the optimal recipe for the treatment of focal cartilage defects. Although many attempts had been made, beyond the use of osteochondral allografts, the restoration of pristine hyaline cartilage still seems distant and out of reach. The fundamental assumption is that cartilage restoration constructs must provide both structural integrity and adequate biological features that provide the optimal environment for hyaline cartilage formation. Augmentation of biologic scaffolds and grafts with orthobiologic agents may attend to both needs by improving defect fill and integration to the host articular cartilage interface.
Identifiants
pubmed: 32370905
pii: S0749-8063(20)30199-7
doi: 10.1016/j.arthro.2020.03.002
pii:
doi:
Substances chimiques
Hyaluronic Acid
9004-61-9
Types de publication
Editorial
Comment
Langues
eng
Sous-ensembles de citation
IM
Pagination
1441-1442Commentaires et corrections
Type : CommentOn
Informations de copyright
Copyright © 2020 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.