A game-theoretical analysis of poliomyelitis vaccination.


Journal

Journal of theoretical biology
ISSN: 1095-8541
Titre abrégé: J Theor Biol
Pays: England
ID NLM: 0376342

Informations de publication

Date de publication:
21 08 2020
Historique:
received: 31 12 2019
revised: 21 04 2020
accepted: 26 04 2020
pubmed: 7 5 2020
medline: 22 6 2021
entrez: 7 5 2020
Statut: ppublish

Résumé

Poliomyelitis is a worldwide disease that has nearly been eradicated thanks to the Global Polio Eradication Initiative. Nevertheless, the disease is currently still endemic in three countries. In this paper, we incorporate the vaccination in a two age-class model of polio dynamics. Our main objective is to see whether mandatory vaccination policy is needed or if polio could be almost eradicated by a voluntary vaccination. We perform game theoretical analysis and compare the herd immunity vaccination levels with the Nash equilibrium vaccination levels. We show that the gap between two vaccination levels is too large. We conclude that the mandatory vaccination policy is therefore needed to achieve a complete eradication.

Identifiants

pubmed: 32371008
pii: S0022-5193(20)30153-3
doi: 10.1016/j.jtbi.2020.110298
pii:
doi:

Substances chimiques

Poliovirus Vaccine, Oral 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

110298

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Emily Cheng (E)

Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23284-3068, USA. Electronic address: chenge3@vcu.edu.

Neeha Gambhirrao (N)

Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23284-3068, USA. Electronic address: gambhirraon@vcu.edu.

Rohani Patel (R)

Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23284-3068, USA. Electronic address: patelra23@vcu.edu.

Aufia Zhowandai (A)

Department of Biology, Virginia Commonwealth University, Richmond, VA 23284-2012, USA. Electronic address: zhowandaiai@vcu.edu.

Jan Rychtář (J)

Department of Mathematics and Applied Mathematics, Virginia Commonwealth University, Richmond, VA 23284-2014, USA. Electronic address: rychtarj@vcu.edu.

Dewey Taylor (D)

Department of Mathematics and Applied Mathematics, Virginia Commonwealth University, Richmond, VA 23284-2014, USA. Electronic address: dttaylor2@vcu.edu.

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Classifications MeSH