Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33.

ADAM metallopeptidase domain 10 (ADAM10) PDZ domain containing 11 (PDZD11) PDZD11 PLEKHA7 Pleckstrin homology domain containing A7 (PLEKHA7) WW domain adherens junction cell-cell junction cooperativity membrane protein molecular docking polyproline protein complex tetraspanin 33 tetraspanin33 α-toxin

Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
10 07 2020
Historique:
received: 11 02 2020
revised: 30 04 2020
pubmed: 7 5 2020
medline: 14 1 2021
entrez: 7 5 2020
Statut: ppublish

Résumé

Pleckstrin homology domain-containing A7 (PLEKHA7) is a cytoplasmic protein at adherens junctions that has been implicated in hypertension, glaucoma, and responses to

Identifiants

pubmed: 32371390
pii: S0021-9258(17)48954-X
doi: 10.1074/jbc.RA120.012987
pmc: PMC7363125
doi:

Substances chimiques

Carrier Proteins 0
PDZD11 protein, human 0
PLEKHA7 protein, human 0
TSPAN33 protein, human 0
Tetraspanins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9299-9312

Informations de copyright

© 2020 Rouaud et al.

Déclaration de conflit d'intérêts

Conflict of interest—The authors declare that they have no conflict of interest with the contents of this article.

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Auteurs

Florian Rouaud (F)

Department of Cell Biology, Faculty of Sciences, University of Geneva, Geneva, Switzerland.
The Institute for Genetics and Genomics in Geneva (iGE3), University of Geneva, Geneva, Switzerland.

Francesca Tessaro (F)

The Pharmaceutical Biochemistry Group, School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.

Laura Aimaretti (L)

The Pharmaceutical Biochemistry Group, School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.

Leonardo Scapozza (L)

The Pharmaceutical Biochemistry Group, School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.

Sandra Citi (S)

Department of Cell Biology, Faculty of Sciences, University of Geneva, Geneva, Switzerland sandra.citi@unige.ch.
The Institute for Genetics and Genomics in Geneva (iGE3), University of Geneva, Geneva, Switzerland.

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Classifications MeSH