Human Cerebrospinal Fluid Induces Neuronal Excitability Changes in Resected Human Neocortical and Hippocampal Brain Slices.

CMOS-MEA cortex hippocampus human cerebrospinal fluid human tissue microelectrode array organotypic slices

Journal

Frontiers in neuroscience
ISSN: 1662-4548
Titre abrégé: Front Neurosci
Pays: Switzerland
ID NLM: 101478481

Informations de publication

Date de publication:
2020
Historique:
received: 02 10 2019
accepted: 12 03 2020
entrez: 7 5 2020
pubmed: 7 5 2020
medline: 7 5 2020
Statut: epublish

Résumé

Human cerebrospinal fluid (hCSF) has proven advantageous over conventional medium for culturing both rodent and human brain tissue. In addition, increased activity and synchrony, closer to the dynamic states exclusively recorded

Identifiants

pubmed: 32372899
doi: 10.3389/fnins.2020.00283
pmc: PMC7186381
doi:

Types de publication

Journal Article

Langues

eng

Pagination

283

Informations de copyright

Copyright © 2020 Wickham, Corna, Schwarz, Uysal, Layer, Honegger, Wuttke, Koch and Zeck.

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Auteurs

Jenny Wickham (J)

Neurophysics, Natural and Medical Sciences Institute, University of Tübingen, Reutlingen, Germany.

Andrea Corna (A)

Neurophysics, Natural and Medical Sciences Institute, University of Tübingen, Reutlingen, Germany.
Graduate School of Neural Information Processing/International Max Planck Research School, Tübingen, Germany.
Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany.

Niklas Schwarz (N)

Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

Betül Uysal (B)

Graduate School of Neural Information Processing/International Max Planck Research School, Tübingen, Germany.
Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

Nikolas Layer (N)

Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

Jürgen B Honegger (JB)

Department of Neurosurgery, University of Tübingen, Tübingen, Germany.

Thomas V Wuttke (TV)

Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Department of Neurosurgery, University of Tübingen, Tübingen, Germany.

Henner Koch (H)

Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Department of Epileptology, Neurology, RWTH Aachen University, Aachen, Germany.

Günther Zeck (G)

Neurophysics, Natural and Medical Sciences Institute, University of Tübingen, Reutlingen, Germany.

Classifications MeSH