Organic anion transporters also mediate the drug-drug interaction between imipenem and cilastatin.
Drug–drug interaction
Imipenem/cilastatin
Organic anion transporters
Renal dipeptidase
Journal
Asian journal of pharmaceutical sciences
ISSN: 2221-285X
Titre abrégé: Asian J Pharm Sci
Pays: Netherlands
ID NLM: 101535338
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
29
06
2018
revised:
03
10
2018
accepted:
17
11
2018
entrez:
7
5
2020
pubmed:
7
5
2020
medline:
7
5
2020
Statut:
ppublish
Résumé
This study aimed to clarify that organic anion transporters (OATs) mediate the drug-drug interaction (DDI) between imipenem and cilastatin. After co-administration with imipenem, the plasma concentrations and the plasma concentration-time curve (
Identifiants
pubmed: 32373203
doi: 10.1016/j.ajps.2018.11.006
pii: S1818-0876(18)30634-2
pmc: PMC7193450
doi:
Types de publication
Journal Article
Langues
eng
Pagination
252-263Informations de copyright
© 2019 Published by Elsevier B.V. on behalf of Shenyang Pharmaceutical University.
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