Estimated Demand for US Hospital Inpatient and Intensive Care Unit Beds for Patients With COVID-19 Based on Comparisons With Wuhan and Guangzhou, China.


Journal

JAMA network open
ISSN: 2574-3805
Titre abrégé: JAMA Netw Open
Pays: United States
ID NLM: 101729235

Informations de publication

Date de publication:
01 05 2020
Historique:
entrez: 7 5 2020
pubmed: 7 5 2020
medline: 13 5 2020
Statut: epublish

Résumé

Sustained spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has happened in major US cities. Capacity needs in cities in China could inform the planning of local health care resources. To describe and compare the intensive care unit (ICU) and inpatient bed needs for patients with coronavirus disease 2019 (COVID-19) in 2 cities in China to estimate the peak ICU bed needs in US cities if an outbreak equivalent to that in Wuhan occurs. This comparative effectiveness study analyzed the confirmed cases of COVID-19 in Wuhan and Guangzhou, China, from January 10 to February 29, 2020. Timing of disease control measures relative to timing of SARS-CoV-2 community spread. Number of critical and severe patient-days and peak number of patients with critical and severe illness during the study period. In Wuhan, strict disease control measures were implemented 6 weeks after sustained local transmission of SARS-CoV-2. Between January 10 and February 29, 2020, patients with COVID-19 accounted for a median (interquartile range) of 429 (25-1143) patients in the ICU and 1521 (111-7202) inpatients with serious illness each day. During the epidemic peak, 19 425 patients (24.5 per 10 000 adults) were hospitalized, 9689 (12.2 per 10 000 adults) were considered in serious condition, and 2087 (2.6 per 10 000 adults) needed critical care per day. In Guangzhou, strict disease control measures were implemented within 1 week of case importation. Between January 24 and February 29, COVID-19 accounted for a median (interquartile range) of 9 (7-12) patients in the ICU and 17 (15-26) inpatients with serious illness each day. During the epidemic peak, 15 patients were in critical condition and 38 were classified as having serious illness. The projected number of prevalent critically ill patients at the peak of a Wuhan-like outbreak in US cities was estimated to range from 2.2 to 4.4 per 10 000 adults, depending on differences in age distribution and comorbidity (ie, hypertension) prevalence. Even after the lockdown of Wuhan on January 23, the number of patients with serious COVID-19 illness continued to rise, exceeding local hospitalization and ICU capacities for at least a month. Plans are urgently needed to mitigate the consequences of COVID-19 outbreaks on the local health care systems in US cities.

Identifiants

pubmed: 32374400
pii: 2765575
doi: 10.1001/jamanetworkopen.2020.8297
pmc: PMC7203604
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

e208297

Subventions

Organisme : NIGMS NIH HHS
ID : U54 GM088558
Pays : United States
Organisme : CDC HHS
ID : CK000538-01
Pays : United States

Références

Value Health. 2009 Nov-Dec;12(8):1044-52
pubmed: 19793072
JAMA. 2010 Apr 14;303(14):1371-2
pubmed: 20388892
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Feb 17;41(2):145-151
pubmed: 32064853
JAMA. 2020 Feb 24;:
pubmed: 32091533
JAMA. 2007 Aug 8;298(6):644-54
pubmed: 17684187
Proc Natl Acad Sci U S A. 2007 May 1;104(18):7582-7
pubmed: 17416679
Intensive Care Med. 2020 Apr;46(4):579-582
pubmed: 32103284
Crit Care Med. 2013 Dec;41(12):2712-9
pubmed: 23963122
Science. 2020 May 1;368(6490):493-497
pubmed: 32213647
Lancet. 2020 Mar 14;395(10227):848-850
pubmed: 32151326

Auteurs

Ruoran Li (R)

Harvard T.H. Chan School of Public Health, Center for Communicable Disease Dynamics, Department of Epidemiology, Boston, Massachusetts.

Caitlin Rivers (C)

Johns Hopkins Bloomberg School of Public Health, Johns Hopkins Center for Health Security and the Department of Environmental Health and Engineering, Baltimore, Maryland.

Qi Tan (Q)

Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts.
Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China.

Megan B Murray (MB)

Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts.

Eric Toner (E)

Johns Hopkins Bloomberg School of Public Health, Johns Hopkins Center for Health Security and the Department of Environmental Health and Engineering, Baltimore, Maryland.

Marc Lipsitch (M)

Harvard T.H. Chan School of Public Health, Center for Communicable Disease Dynamics, Department of Epidemiology, Boston, Massachusetts.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH