Breakthrough Pain in Patients with Lung Cancer. A Secondary Analysis of IOPS MS Study.

Breakthrough cancer pain Lung cancer Opioids cancer pain

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
04 May 2020
Historique:
received: 10 04 2020
revised: 24 04 2020
accepted: 28 04 2020
entrez: 8 5 2020
pubmed: 8 5 2020
medline: 8 5 2020
Statut: epublish

Résumé

To characterize breakthrough cancer pain (BTcP) in patients with lung cancer. This was a secondary analysis of multicenter study of patients with BTcP. Background pain intensity and opioid dose were recorded. The number of BTcP episodes, their intensity, predictability, onset, duration and interference with daily activities were collected. Opioids used for BTcP, the mean time to meaningful pain relief after taking medication, satisfaction and adverse effects were assessed. 1087 patients with lung cancer were examined. In comparison with other tumors, patients with lung cancer showed: higher background pain intensity ( Patients with lung cancer have their own peculiarities, including higher basal and BTcP pain intensity and the use of more adjuvant drugs for background pain. The most frequent triggers for predictable BTcP are movement and cough. Future studies should be performed to analyze the prevalence of BTcP in patients with different lung cancers as well as the optimal management strategy for background pain and BTcP.

Identifiants

pubmed: 32375331
pii: jcm9051337
doi: 10.3390/jcm9051337
pmc: PMC7290905
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Sebastiano Mercadante (S)

Main Regional Center for Pain, Pain Relief and Supportive/Palliative Care, La Maddalena Cancer Center, 90146 Palermo, Italy.

Francesco Masedu (F)

Department of Biotechnological and Applied Clinical Sciences, Section of Clinical Epidemiology and Environmental Medicine, University of L'Aquila, 67100 L'Aquila, Italy.

Marco Valenti (M)

Department of Biotechnological and Applied Clinical Sciences, Section of Clinical Epidemiology and Environmental Medicine, University of L'Aquila, 67100 L'Aquila, Italy.

Federica Aielli (F)

Department of Medical Oncology, AUSL Teramo, 64100 Teramo, Italy.

Classifications MeSH