Cnf1 Variants Endowed with the Ability to Cross the Blood-Brain Barrier: A New Potential Therapeutic Strategy for Glioblastoma.
Animals
Antineoplastic Agents
/ metabolism
Bacterial Toxins
/ genetics
Blood-Brain Barrier
/ metabolism
Brain Neoplasms
/ drug therapy
Capillary Permeability
Cell Line, Tumor
Cell Proliferation
/ drug effects
Escherichia coli Proteins
/ genetics
Glioblastoma
/ drug therapy
Humans
Male
Mice, Inbred C57BL
Signal Transduction
cytotoxic necrotizing factor type 1
drug discovery
glioblastoma
protein purification
recombinant protein production
Journal
Toxins
ISSN: 2072-6651
Titre abrégé: Toxins (Basel)
Pays: Switzerland
ID NLM: 101530765
Informations de publication
Date de publication:
04 05 2020
04 05 2020
Historique:
received:
14
04
2020
revised:
30
04
2020
accepted:
02
05
2020
entrez:
8
5
2020
pubmed:
8
5
2020
medline:
3
3
2021
Statut:
epublish
Résumé
Among gliomas, primary tumors originating from glial cells, glioblastoma (GBM) identified as WHO grade IV glioma, is the most common and aggressive malignant brain tumor. We have previously shown that the
Identifiants
pubmed: 32375387
pii: toxins12050291
doi: 10.3390/toxins12050291
pmc: PMC7290510
pii:
doi:
Substances chimiques
Antineoplastic Agents
0
Bacterial Toxins
0
Escherichia coli Proteins
0
cytotoxic necrotizing factor type 1
106803-33-2
Types de publication
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : La fabbrica dei sogni 2 - New developments for Rett syndrome
ID : ---
Pays : International
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