A surrogate FRAX model for the Kyrgyz Republic.
Epidemiology
FRAX
Fracture probability
Hip fracture
Kazakhstan
Kyrgyz Republic
Surrogate
Journal
Archives of osteoporosis
ISSN: 1862-3514
Titre abrégé: Arch Osteoporos
Pays: England
ID NLM: 101318988
Informations de publication
Date de publication:
06 05 2020
06 05 2020
Historique:
received:
28
02
2020
accepted:
27
04
2020
entrez:
8
5
2020
pubmed:
8
5
2020
medline:
1
12
2020
Statut:
epublish
Résumé
The hip fracture rates from Kazakhstan were used to create a surrogate FRAX® model for the Kyrgyz Republic. The International Society for Clinical Densitometry and International Osteoporosis Foundation recommend utilizing a surrogate FRAX model, based on the country-specific risk of death, and fracture data based on a country where fracture rates are considered to be representative of the index country. This paper describes a surrogate FRAX model for the Kyrgyz Republic. The FRAX model used the incidence of hip fracture from the neighbouring country of Kazakhstan and the death risk for the Kyrgyz Republic. Compared with the model for Kazakhstan, the surrogate model gave somewhat higher 10-year fracture probabilities for men between 60 and 80 years of age and lower probabilities for men above the age of 80. For women the probabilities were similar up to the age of 75-80 years and then lower. There were very close correlations in fracture probabilities between the surrogate and authentic models (1.00) so that the use of the Kyrgyz model had little impact on the rank order of risk. It was estimated that 2752 hip fractures arose in 2015 in individuals over the age of 50 years in the Kyrgyz Republic, with a predicted increase by 207% to 8435 in 2050. The surrogate FRAX model for the Kyrgyz Republic provides the opportunity to determine fracture probability among the Kyrgyz population and help guide decisions about treatment.
Identifiants
pubmed: 32377964
doi: 10.1007/s11657-020-00743-2
pii: 10.1007/s11657-020-00743-2
pmc: PMC7203583
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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