COVID-19: Postmortem Diagnostic and Biosafety Considerations.
Autopsy
/ standards
Betacoronavirus
/ genetics
COVID-19
Centers for Disease Control and Prevention, U.S.
Containment of Biohazards
/ standards
Coronavirus Infections
/ mortality
Female
Humans
Middle Aged
Mortuary Practice
/ methods
Pandemics
Pneumonia, Viral
/ mortality
Real-Time Polymerase Chain Reaction
/ standards
SARS-CoV-2
Triage
United States
Journal
The American journal of forensic medicine and pathology
ISSN: 1533-404X
Titre abrégé: Am J Forensic Med Pathol
Pays: United States
ID NLM: 8108948
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
pubmed:
8
5
2020
medline:
21
8
2020
entrez:
8
5
2020
Statut:
ppublish
Résumé
As a result of the 2019 novel human coronavirus (COVID-19) global spread, medical examiner/coroner offices will inevitably encounter increased numbers of COVID-19-infected decedents at autopsy. While in some cases a history of fever and/or respiratory distress (eg, cough or shortness of breath) may suggest the diagnosis, epidemiologic studies indicate that the majority of individuals infected with COVID-19 develop mild to no symptoms. Those dying with-but not of-COVID-19 may still be infectious, however. While multiple guidelines have been issued regarding autopsy protocol in cases of suspected COVID-19 deaths, there is some variability in the recommendations. Additionally, limited recommendations to date have been issued regarding scene investigative protocol, and there is a paucity of publications characterizing COVID-19 postmortem gross and histologic findings. A case of sudden unexpected death due to COVID-19 is presented as a means of illustrating common autopsy findings, as well as diagnostic and biosafety considerations. We also review and summarize the current COVID-19 literature in an effort to provide practical evidence-based biosafety guidance for medical examiner-coroner offices encountering COVID-19 at autopsy.
Identifiants
pubmed: 32379077
doi: 10.1097/PAF.0000000000000567
pmc: PMC7202125
pii: 00000433-202009000-00001
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
143-151Commentaires et corrections
Type : CommentIn
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