Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer.
Brachytherapy
Breast cancer
Early breast cancer
Partial breast irradiation
Journal
Breast (Edinburgh, Scotland)
ISSN: 1532-3080
Titre abrégé: Breast
Pays: Netherlands
ID NLM: 9213011
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
received:
12
12
2019
revised:
31
03
2020
accepted:
18
04
2020
pubmed:
8
5
2020
medline:
20
3
2021
entrez:
8
5
2020
Statut:
ppublish
Résumé
Patients with low-risk invasive ductal carcinoma treated with breast-conserving surgery (BCS) were included in a multicatheter brachytherapy APBI protocol. The primary endpoint was ipsilateral breast recurrence. Between December 2008-December 2017, 186 low-risk breast cancer patients were treated with APBI using interstitial multicatheter brachytherapy and followed prospectively. At 5-years of follow-up, cumulative local recurrence (LR) and cause-specific survival was 1.1% (95% CI 0.3-1.9) and 98.3% (95% CI 97.3-99.3%) respectively. No grade 3 adverse effects were observed. Postoperative APBI using multicatheter brachytherapy after BCS in early breast cancer patients have excellent rates of local control and survival, without significant toxicity.
Identifiants
pubmed: 32380439
pii: S0960-9776(20)30102-8
doi: 10.1016/j.breast.2020.04.008
pmc: PMC7375648
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
45-49Informations de copyright
Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare no conflict of interest.
Références
Lancet Oncol. 2018 Jun;19(6):834-844
pubmed: 29695348
Lancet. 2011 Nov 12;378(9804):1707-16
pubmed: 22019144
Radiother Oncol. 2013 Aug;108(2):197-202
pubmed: 23742961
Radiother Oncol. 2010 Mar;94(3):274-9
pubmed: 20181401
N Engl J Med. 2010 Feb 11;362(6):513-20
pubmed: 20147717
Radiother Oncol. 2018 Sep;128(3):411-420
pubmed: 29691075
Brachytherapy. 2013 Jul-Aug;12(4):267-77
pubmed: 23619524
Lancet. 2005 Dec 17;366(9503):2087-106
pubmed: 16360786
Int J Radiat Oncol Biol Phys. 2011 May 1;80(1):17-24
pubmed: 20605365
Lancet Oncol. 2013 Oct;14(11):1086-1094
pubmed: 24055415
Radiother Oncol. 2009 Jan;90(1):1-13
pubmed: 18783840
Int J Radiat Oncol Biol Phys. 2011 Mar 1;79(3):641-9
pubmed: 21106308
Radiother Oncol. 2014 Jul;112(1):9-16
pubmed: 24813095
Lancet Oncol. 2015 Jan;16(1):47-56
pubmed: 25500422
Lancet. 2016 Jan 16;387(10015):229-38
pubmed: 26494415
Lancet Oncol. 2017 Feb;18(2):259-268
pubmed: 28094198
Radiother Oncol. 2016 Jan;118(1):199-204
pubmed: 26776444
Int J Radiat Oncol Biol Phys. 2007 Jun 1;68(2):334-40
pubmed: 17363187
Brachytherapy. 2018 Jan - Feb;17(1):154-170
pubmed: 29074088
Pract Radiat Oncol. 2017 Mar - Apr;7(2):73-79
pubmed: 27866865
J Am Coll Surg. 2009 Aug;209(2):269-77
pubmed: 19632605