Colorectal Adenomas-Genetics and Searching for New Molecular Screening Biomarkers.
biomarkers
colorectal adenoma
colorectal cancer
early detection
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
05 May 2020
05 May 2020
Historique:
received:
25
04
2020
revised:
01
05
2020
accepted:
02
05
2020
entrez:
9
5
2020
pubmed:
10
5
2020
medline:
9
2
2021
Statut:
epublish
Résumé
Colorectal cancer (CRC) is a malignant disease with an incidence of over 1.8 million new cases per year worldwide. CRC outcome is closely related to the respective stage of CRC and is more favorable at less advanced stages. Detection of early colorectal adenomas is the key to survival. In spite of implemented screening programs showing efficiency in the detection of early precancerous lesions and CRC in asymptomatic patients, a significant number of patients are still diagnosed in advanced stages. Research on CRC accomplished during the last decade has improved our understanding of the etiology and development of colorectal adenomas and revealed weaknesses in the general approach to their detection and elimination. Recent studies seek to find a reliable non-invasive biomarker detectable even in the blood. New candidate biomarkers could be selected on the basis of so-called liquid biopsy, such as long non-coding RNA, microRNA, circulating cell-free DNA, circulating tumor cells, and inflammatory factors released from the adenoma into circulation. In this work, we focused on both genetic and epigenetic changes associated with the development of colorectal adenomas into colorectal carcinoma and we also discuss new possible biomarkers that are detectable even in adenomas prior to cancer development.
Identifiants
pubmed: 32380676
pii: ijms21093260
doi: 10.3390/ijms21093260
pmc: PMC7247353
pii:
doi:
Substances chimiques
Biomarkers, Tumor
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Grant Agency of the Ministry of Health of the Czech Republic
ID : AZVNV18-03-00199
Organisme : Grant Agency of the Czech Republic
ID : GACR18-09709S
Organisme : Charles University Grant Agency
ID : GAUK 302119
Organisme : European Cooperation in Science and Technology
ID : CA17118
Références
Tumour Biol. 2014 Dec;35(12):12181-8
pubmed: 25185650
Pathobiology. 2015;82(5):233-41
pubmed: 26389729
Am J Pathol. 2001 Sep;159(3):1129-35
pubmed: 11549606
Clin Cancer Res. 2014 Jun 1;20(11):2994-3002
pubmed: 24691020
J Natl Cancer Inst. 2000 Jun 7;92(11):918-23
pubmed: 10841827
N Engl J Med. 2008 Sep 18;359(12):1207-17
pubmed: 18799557
BMC Med Genomics. 2017 Apr 20;10(1):23
pubmed: 28427387
Mutat Res. 2019 Jul - Sep;781:100-129
pubmed: 31416571
Gut. 2007 Nov;56(11):1585-9
pubmed: 17591622
Int J Cancer. 2014 Dec 1;135(11):2507-15
pubmed: 24752710
Endoscopy. 2002 Mar;34(3):226-36
pubmed: 11870575
BMC Cancer. 2019 May 14;19(1):450
pubmed: 31088406
Sci Rep. 2019 Jul 1;9(1):9491
pubmed: 31263200
Curr Treat Options Gastroenterol. 2016 Mar;14(1):152-62
pubmed: 26825703
Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3352-7
pubmed: 10737795
Virchows Arch. 2016 Aug;469(2):125-34
pubmed: 27325016
Future Oncol. 2018 Jun;14(13):1307-1316
pubmed: 29741114
Dtsch Arztebl Int. 2013 Jan;110(3):32-8
pubmed: 23413378
Br J Cancer. 2014 Nov 11;111(10):1985-92
pubmed: 25233400
Cancer Med. 2018 Jan;7(1):167-174
pubmed: 29125240
Int J Surg. 2015 Jan;13:272-279
pubmed: 25496852
Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8681-6
pubmed: 10411935
Cancer Biol Med. 2016 Mar;13(1):120-35
pubmed: 27144067
Biochim Biophys Acta. 2007 Jan;1775(1):181-232
pubmed: 17137717
Eur J Cancer Prev. 2016 May;25(3):173-81
pubmed: 25793917
World J Gastroenterol. 2012 Mar 21;18(11):1185-90
pubmed: 22468081
N Engl J Med. 1998 Oct 29;339(18):1277-84
pubmed: 9791143
Nat Rev Clin Oncol. 2013 Aug;10(8):472-84
pubmed: 23836314
Rev Esp Enferm Dig. 2009 Mar;101(3):179-86
pubmed: 19388798
Nature. 1986 May 15-21;321(6067):209-13
pubmed: 2423876
PLoS One. 2011;6(6):e20465
pubmed: 21694772
Mol Aspects Med. 2019 Oct;69:107-122
pubmed: 31189073
Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):1999-2004
pubmed: 23345422
Sci Rep. 2017 Jun 8;7(1):3032
pubmed: 28596563
Ann N Y Acad Sci. 2000 Apr;906:44-50
pubmed: 10818595
Transl Res. 2015 Sep;166(3):225-232
pubmed: 25770825
Science. 2015 May 22;348(6237):880-6
pubmed: 25999502
Nature. 2012 Sep 6;489(7414):101-8
pubmed: 22955620
World J Gastrointest Oncol. 2016 Jul 15;8(7):532-42
pubmed: 27559432
Cell Death Dis. 2017 Jun 8;8(6):e2862
pubmed: 28594403
Pathology. 2012 Feb;44(2):80-8
pubmed: 22198259
Eur J Cancer Prev. 2015 Jul;24(4):296-304
pubmed: 25350634
J Natl Cancer Inst. 1994 Jul 6;86(13):1007-10
pubmed: 8007010
Eur J Cancer. 2015 Feb;51(3):409-20
pubmed: 25586944
Oncotarget. 2018 Feb 7;9(17):13582-13592
pubmed: 29568379
EBioMedicine. 2016 Nov;13:113-124
pubmed: 27789274
Gastroenterology. 2002 Oct;123(4):1109-19
pubmed: 12360473
Carcinogenesis. 2019 Jul 6;40(6):765-770
pubmed: 30753331
Biomed Rep. 2018 Aug;9(2):181-186
pubmed: 30083318
Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12417-22
pubmed: 18719115
Nature. 1997 Apr 24;386(6627):761, 763
pubmed: 9126728
Tumori. 2014 Mar-Apr;100(2):115-21
pubmed: 24852853
Oncol Lett. 2019 Feb;17(2):2531-2542
pubmed: 30675315
Gastroenterology. 2020 Jan;158(2):418-432
pubmed: 31394083
BMC Cancer. 2014 Dec 18;14:976
pubmed: 25519477
Mol Med Rep. 2019 Feb;19(2):771-782
pubmed: 30535444
World J Gastroenterol. 2010 Jul 28;16(28):3553-60
pubmed: 20653064
Mol Clin Oncol. 2019 Aug;11(2):201-207
pubmed: 31316774
J Hematol Oncol. 2013 May 31;6:37
pubmed: 23725405
Prz Gastroenterol. 2019;14(2):89-103
pubmed: 31616522
J Cancer Res Clin Oncol. 2020 Jan;146(1):205-219
pubmed: 31620896
PLoS One. 2015 Jul 06;10(7):e0132495
pubmed: 26148070
Cell. 2017 Feb 9;168(4):571-574
pubmed: 28187279
Nat Genet. 2013 Oct;45(10):1127-33
pubmed: 24071851
Br J Cancer. 2019 Aug;121(4):344-350
pubmed: 31312029
Ann Surg. 2013 Sep;258(3):400-8
pubmed: 24022433
Mol Oncol. 2016 Mar;10(3):374-94
pubmed: 26897752
PLoS One. 2014 Aug 11;9(8):e104284
pubmed: 25111606
Front Endocrinol (Lausanne). 2018 Aug 03;9:402
pubmed: 30123182
Hum Mol Genet. 2014 Sep 1;23(17):4729-37
pubmed: 24737748
Genes Cancer. 2011 Aug;2(8):829-40
pubmed: 22393467
Oncotarget. 2016 Dec 20;7(51):85551-85563
pubmed: 27888803
Nat Rev Clin Oncol. 2018 Mar;15(3):139-150
pubmed: 29297505
J Cancer Res Clin Oncol. 2020 May;146(5):1273-1290
pubmed: 32088781
Clin Cancer Res. 2017 Oct 1;23(19):5936-5947
pubmed: 28645942
Am J Surg. 2014 May;207(5):717-22; discussion 722
pubmed: 24791633
N Engl J Med. 1993 May 13;328(19):1365-71
pubmed: 8474513
Gastrointest Endosc. 2010 Apr;71(4):792-8
pubmed: 20363421
Ann Oncol. 2015 Mar;26(3):535-41
pubmed: 25515656
Br J Cancer. 2011 Jul 12;105(2):239-45
pubmed: 21712823
Lancet. 2010 May 8;375(9726):1624-33
pubmed: 20430429
Nature. 2012 Sep 6;489(7414):57-74
pubmed: 22955616
J Korean Med Sci. 2002 Jun;17(3):360-5
pubmed: 12068140
Sci Transl Med. 2014 Feb 19;6(224):224ra24
pubmed: 24553385
Science. 2013 Oct 04;342(6154):1235587
pubmed: 24092746
Int J Cancer. 2000 Jan 20;89(1):8-13
pubmed: 10719724
PLoS One. 2016 Oct 19;11(10):e0160722
pubmed: 27760147
Cancer Res. 1997 Jun 15;57(12):2485-92
pubmed: 9192830
Gastroenterol Hepatol Bed Bench. 2013 Summer;6(3):120-8
pubmed: 24834258
Front Genet. 2018 Dec 18;9:640
pubmed: 30619465
World J Gastroenterol. 2014 Jun 14;20(22):6786-808
pubmed: 24944469
Gastroenterology. 2010 Jun;138(6):2073-2087.e3
pubmed: 20420947
Gastroenterol Rep (Oxf). 2014 Feb;2(1):1-15
pubmed: 24760231
Adv Exp Med Biol. 2009;656:85-106
pubmed: 19928355
Gastroenterology. 2010 Apr;138(4):1441-54, 1454.e1-7
pubmed: 20102718
PLoS One. 2018 Oct 17;13(10):e0205697
pubmed: 30332457
Clin Gastroenterol Hepatol. 2013 Oct;11(10):1313-8
pubmed: 23639600
Cancer Prev Res (Phila). 2016 Dec;9(12):942-949
pubmed: 27658891
Nat Rev Dis Primers. 2015 Nov 05;1:15065
pubmed: 27189416
CA Cancer J Clin. 2006 May-Jun;56(3):143-59; quiz 184-5
pubmed: 16737947
Patholog Res Int. 2011 Apr 12;2011:902674
pubmed: 21559209
N Engl J Med. 2014 Apr 3;370(14):1287-97
pubmed: 24645800
JAMA. 2008 Jan 30;299(4):425-36
pubmed: 18230780
Gastroenterology. 2020 Apr;158(5):1274-1286.e12
pubmed: 31866242
Colorectal Dis. 2013 Jan;15(1):74-9
pubmed: 22672571
Cancer Epidemiol. 2015 Apr;39(2):160-5
pubmed: 25592235
J Clin Pathol. 2014 Oct;67(10):848-53
pubmed: 25008452
Int J Cancer. 2004 Sep 10;111(4):633-9
pubmed: 15239144
Anticancer Res. 2017 Feb;37(2):651-657
pubmed: 28179313
Mutagenesis. 2020 Feb 21;:
pubmed: 32083302
BMC Cancer. 2015 Apr 30;15:329
pubmed: 25924769
Clin Epigenetics. 2017 Feb 14;9:22
pubmed: 28289479
J Cancer Res Ther. 2019;15(2):278-285
pubmed: 30964098
Mol Aspects Med. 2019 Oct;69:73-92
pubmed: 31028771
Nat Commun. 2014 Nov 14;5:5457
pubmed: 25394515
Clin Transl Gastroenterol. 2019 Oct;10(10):e00088
pubmed: 31663904
Nat Genet. 2007 Apr;39(4):457-66
pubmed: 17334365
Carcinogenesis. 2010 Mar;31(3):350-8
pubmed: 19926638
BMC Cancer. 2013 Apr 17;13:196
pubmed: 23594791
Am J Pathol. 1999 Dec;155(6):1849-53
pubmed: 10595914
Cancer. 2018 Feb 15;124(4):785-796
pubmed: 29112225
N Engl J Med. 1993 Dec 30;329(27):1977-81
pubmed: 8247072
Oncotarget. 2016 Jun 14;7(24):36474-36488
pubmed: 27167335
Cell Death Dis. 2018 Aug 30;9(9):894
pubmed: 30166531
Carcinogenesis. 2014 Jul;35(7):1510-5
pubmed: 24583926
Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18545-50
pubmed: 20876136
Genes Chromosomes Cancer. 2019 Jan;58(1):23-33
pubmed: 30265426
Nat Ecol Evol. 2018 Oct;2(10):1661-1672
pubmed: 30177804
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Curr Probl Cancer. 2018 Jan - Feb;42(1):95-106
pubmed: 29277243
Nature. 2013 Feb 28;494(7438):492-496
pubmed: 23446422
Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4589-94
pubmed: 9539782
BMC Cancer. 2015 Mar 14;15:123
pubmed: 25884547
Gastroenterol Res Pract. 2018 Jun 13;2018:2397863
pubmed: 30008744
Br J Cancer. 2009 Aug 18;101(4):707-14
pubmed: 19672269
Am J Pathol. 2003 Mar;162(3):815-22
pubmed: 12598316
Cell Physiol Biochem. 2017;41(6):2489-2502
pubmed: 28472810
Cancer Prev Res (Phila). 2014 Jun;7(6):607-16
pubmed: 24691499
Mol Clin Oncol. 2019 Aug;11(2):167-172
pubmed: 31281651
World J Gastroenterol. 2017 Mar 14;23(10):1909-1919
pubmed: 28348498
CA Cancer J Clin. 2008 May-Jun;58(3):130-60
pubmed: 18322143
World J Gastroenterol. 2019 Sep 14;25(34):5026-5048
pubmed: 31558855
Hum Mol Genet. 2001 Apr;10(7):735-40
pubmed: 11257106
Endoscopy. 2013 Oct;45(10):842-51
pubmed: 24030244
Int J Mol Sci. 2018 Dec 27;20(1):
pubmed: 30591675
J Natl Cancer Inst. 2013 Aug 21;105(16):1202-11
pubmed: 23918447