Treatment of Infected Tibial Non-Unions with Ilizarov Technique: A Case Series.
ASAMI scoring system
Cierny–Mader classification
Ilizarov technique
bioactive glass
infected tibial non-union
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
05 May 2020
05 May 2020
Historique:
received:
06
04
2020
revised:
26
04
2020
accepted:
02
05
2020
entrez:
9
5
2020
pubmed:
10
5
2020
medline:
10
5
2020
Statut:
epublish
Résumé
The Ilizarov external fixation technique has been widely used for the treatment of long-bone infected non-unions. After surgical infected bone resection, to allow filling of the remaining bone gap, biomaterials with antibacterial properties could be used. The aim of this study was to report outcomes of infected tibial non-unions treated using the Ilizarov technique and antibacterial bioactive glass. Between April 2009 and December 2014, 26 patients with infected tibial non-unions were treated with the Ilizarov technique and possible use of the bioactive glass, S53P4. The Association for the Study and Application of Methods of Ilizarov (ASAMI) criteria, a clinical and radiographic evaluating tool, was used for assessing the sample. The average age at the start of treatment was 51 years. The mean follow-up time was 113 weeks. According to the ASAMI Functional Scoring System, 10 excellent (38.5%) cases and 12 good (46.1%) values were recorded. According to the ASAMI Radiological System, they were excellent in 16 (61.5%) cases and good in nine (34.6%). Treatment of infected tibial non-unions using the Ilizarov technique was effective in bone segment regeneration. To fill the remaining bone gap, additional bioactive glass S53P4 could be used, allowing a decrease in re-interventions and minimizing complications.
Sections du résumé
BACKGROUND
BACKGROUND
The Ilizarov external fixation technique has been widely used for the treatment of long-bone infected non-unions. After surgical infected bone resection, to allow filling of the remaining bone gap, biomaterials with antibacterial properties could be used. The aim of this study was to report outcomes of infected tibial non-unions treated using the Ilizarov technique and antibacterial bioactive glass.
METHODS
METHODS
Between April 2009 and December 2014, 26 patients with infected tibial non-unions were treated with the Ilizarov technique and possible use of the bioactive glass, S53P4. The Association for the Study and Application of Methods of Ilizarov (ASAMI) criteria, a clinical and radiographic evaluating tool, was used for assessing the sample.
RESULTS
RESULTS
The average age at the start of treatment was 51 years. The mean follow-up time was 113 weeks. According to the ASAMI Functional Scoring System, 10 excellent (38.5%) cases and 12 good (46.1%) values were recorded. According to the ASAMI Radiological System, they were excellent in 16 (61.5%) cases and good in nine (34.6%).
CONCLUSIONS
CONCLUSIONS
Treatment of infected tibial non-unions using the Ilizarov technique was effective in bone segment regeneration. To fill the remaining bone gap, additional bioactive glass S53P4 could be used, allowing a decrease in re-interventions and minimizing complications.
Identifiants
pubmed: 32380709
pii: jcm9051352
doi: 10.3390/jcm9051352
pmc: PMC7291197
pii:
doi:
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Clin Orthop Relat Res. 2003 Sep;(414):7-24
pubmed: 12966271
BMC Infect Dis. 2013 Dec 10;13:584
pubmed: 24325278
Clin Orthop Relat Res. 2004 Feb;(419):4-12
pubmed: 15021125
J Clin Orthop Trauma. 2016 Oct-Dec;7(Suppl 2):201-209
pubmed: 28053385
Indian J Orthop. 2014 Nov;48(6):612-6
pubmed: 25404775
Ir J Med Sci. 2013 Sep;182(3):509-11
pubmed: 23292733
J Tissue Eng. 2018 Jun 04;9:2041731418776819
pubmed: 29899969
Ir J Med Sci. 2014 Sep;183(3):423-8
pubmed: 24166049
Indian J Orthop. 2007 Jul;41(3):198-203
pubmed: 21139744
Infect Dis Clin North Am. 2017 Jun;31(2):325-338
pubmed: 28483044
Acta Orthop Belg. 2010 Dec;76(6):811-20
pubmed: 21302581
Rev Chir Orthop Reparatrice Appar Mot. 2005 Apr;91(2):143-8
pubmed: 15908884
Bone Joint J. 2013 Dec;95-B(12):1673-80
pubmed: 24293599
Acta Biomater. 2011 Jun;7(6):2355-73
pubmed: 21421084
Adv Exp Med Biol. 2017;971:81-92
pubmed: 28050878
Acta Biomater. 2006 Mar;2(2):191-9
pubmed: 16701877
Oper Orthop Traumatol. 2006 Oct;18(4):364-76
pubmed: 17103133
Arch Trauma Res. 2013 Aug;2(2):71-5
pubmed: 24396797
Future Microbiol. 2015;10(8):1293-9
pubmed: 26228640
Injury. 2010 Mar;41(3):294-9
pubmed: 20176169
World J Orthop. 2014 Jan 18;5(1):30-7
pubmed: 24649412
Orthop Traumatol Surg Res. 2010 Oct;96(6):637-45
pubmed: 20832381
Injury. 2000 Sep;31(7):509-17
pubmed: 10908744
J Trauma Manag Outcomes. 2008 Jul 23;2(1):6
pubmed: 18651977
Ortop Traumatol Rehabil. 2017 Apr 12;19(2):111-125
pubmed: 28508762
J Bone Joint Surg Br. 2006 Jul;88(7):928-32
pubmed: 16798998
Orthop Clin North Am. 2010 Apr;41(2):233-9
pubmed: 20399362
Arch Orthop Trauma Surg. 2016 Sep;136(9):1233-1241
pubmed: 27447880
Acta Orthop Belg. 2014 Sep;80(3):426-35
pubmed: 26280618
J Bone Joint Surg Am. 1976 Jun;58(4):453-8
pubmed: 773941
Clin Orthop Relat Res. 1989 Feb;(239):263-85
pubmed: 2912628
Injury. 2011 Sep;42 Suppl 2:S87-90
pubmed: 21723553
Biomaterials. 2001 Jun;22(12):1579-82
pubmed: 11374457
J Ayub Med Coll Abbottabad. 2007 Jul-Sep;19(3):34-6
pubmed: 18444588
Biomaterials. 2000 Mar;21(5):483-7
pubmed: 10674813
J Biomed Mater Res A. 2004 Oct 1;71(1):108-17
pubmed: 15368260
J Clin Med. 2019 Jul 28;8(8):
pubmed: 31357687
Biomaterials. 2005 Nov;26(33):6713-9
pubmed: 15950278
Clin Orthop Relat Res. 1989 Apr;(241):146-65
pubmed: 2924458
Indian J Orthop. 2015 Jul-Aug;49(4):429-35
pubmed: 26229164
Trends Biotechnol. 2016 Dec;34(12):983-992
pubmed: 27481474
Bone Joint J. 2014 Jun;96-B(6):845-50
pubmed: 24891588