Postoperative Fasting Blood Glucose Predicts Prognosis in Stage I-III Colorectal Cancer Patients Undergoing Resection.


Journal

Gastroenterology research and practice
ISSN: 1687-6121
Titre abrégé: Gastroenterol Res Pract
Pays: Egypt
ID NLM: 101475557

Informations de publication

Date de publication:
2020
Historique:
received: 28 10 2019
revised: 25 12 2019
accepted: 28 12 2019
entrez: 9 5 2020
pubmed: 10 5 2020
medline: 10 5 2020
Statut: epublish

Résumé

The relationship between high blood glucose and colorectal cancer (CRC) has been studied, but the role of postoperative fasting blood glucose (FBG) in patients with a prior normal FBG has never been addressed. A total of 120 CRC patients staged I-III were enrolled, and the prognostic value of postoperative FBG for disease-free survival (DFS) was determined by Kaplan-Meier analysis. Univariate and multivariate analyses were conducted to test other clinicopathological parameters, including preoperative hemoglobin (HGB) and the neutrophil-lymphocyte ratio (NLR). By a cut-off point of 5.11 mmol/L, 51 and 69 patients were divided into low postoperative FBG (<5.11 mmol/L) and high postoperative FBG (≥5.11 mmol/L) groups, respectively. A high postoperative FBG was more common in older age ( Postoperative FBG plays a temporal prognostic role for patients with stage I-III CRC with a prior normal FBG, but it is not an independent prognostic factor.

Identifiants

pubmed: 32382263
doi: 10.1155/2020/2482409
pmc: PMC7199537
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2482409

Informations de copyright

Copyright © 2020 Rui Xu et al.

Déclaration de conflit d'intérêts

The authors have no conflicts of interest to declare.

Références

Cell Cycle. 2013 Dec 15;12(24):3759-69
pubmed: 24107633
Eur J Cancer. 2019 Apr;111:1-7
pubmed: 30797014
Scand J Gastroenterol. 2006 Sep;41(9):1079-86
pubmed: 16938722
Breast Cancer Res Treat. 2013 Apr;138(3):951-9
pubmed: 23568483
Korean J Fam Med. 2018 Jan;39(1):42-50
pubmed: 29383211
Med Sci Monit. 2015 Dec 08;21:3825-33
pubmed: 26644185
Lung Cancer. 2012 May;76(2):242-7
pubmed: 22112292
Br J Cancer. 2017 Oct 24;117(9):1405-1411
pubmed: 28873085
Cell Biochem Funct. 2009 Mar;27(2):93-101
pubmed: 19205005
BMC Gastroenterol. 2016 Dec 21;16(1):142
pubmed: 28003023
Gerontology. 2011;57(6):497-501
pubmed: 21411967
Nat Genet. 2019 Jul;51(7):1113-1122
pubmed: 31209394
Medicine (Baltimore). 2014 Nov;93(23):e135
pubmed: 25415667
Oncoimmunology. 2017 Dec 21;7(3):e1356144
pubmed: 29399387
BMC Cancer. 2018 Feb 6;18(1):151
pubmed: 29409475
Mutat Res. 2013 May 15;753(2):76-81
pubmed: 23422045
J Clin Oncol. 2005 Dec 1;23(34):8664-70
pubmed: 16260700
Eur J Gastroenterol Hepatol. 2004 Jun;16(6):593-8
pubmed: 15167162
Am J Gastroenterol. 2009 Sep;104(9):2318-25
pubmed: 19513024
Am J Epidemiol. 2004 Jun 15;159(12):1160-7
pubmed: 15191933
Br J Surg. 1993 Aug;80(8):1047-50
pubmed: 8402064
ScientificWorldJournal. 2012;2012:696329
pubmed: 23125556
Diabetes Technol Ther. 2014 Aug;16(8):524-30
pubmed: 24455985
Oncotarget. 2016 Oct 4;7(40):65247-65256
pubmed: 27533454
Nat Rev Cancer. 2016 Oct;16(10):635-49
pubmed: 27634447
Ann Surg Oncol. 2018 Feb;25(2):431-438
pubmed: 29181680
Future Oncol. 2019 May;15(15):1745-1758
pubmed: 31038364
CA Cancer J Clin. 2016 Mar-Apr;66(2):115-32
pubmed: 26808342
JAMA. 2005 Jan 12;293(2):194-202
pubmed: 15644546
World J Gastroenterol. 2016 Jul 21;22(27):6235-45
pubmed: 27468213
Cancer Manag Res. 2019 Apr 16;11:3265-3274
pubmed: 31114364
Int J Oncol. 2014 Jun;44(6):2077-84
pubmed: 24718784
Arch Intern Med. 2000 Jul 24;160(14):2217
pubmed: 10904467
Onco Targets Ther. 2019 Jul 23;12:5947-5953
pubmed: 31413592
Future Oncol. 2018 May;14(12):1187-1196
pubmed: 29302993

Auteurs

Rui Xu (R)

Department of Oncology, Hainan Hospital of PLA General Hospital, Sanya city, Hainan province 572000, China.

Junhao You (J)

Department of Oncology, Hainan Hospital of PLA General Hospital, Sanya city, Hainan province 572000, China.

Fang Li (F)

Department of Oncology, Hainan Hospital of PLA General Hospital, Sanya city, Hainan province 572000, China.

Bing Yan (B)

Department of Oncology, Hainan Hospital of PLA General Hospital, Sanya city, Hainan province 572000, China.

Classifications MeSH