Investigating the influence of paired-associative stimulation on multi-session skill acquisition and retention in older adults.
Ageing
Metaplasticity
Motor learning
Neuroplasticity
Paired-associative stimulation
Transcranial magnetic stimulation
Journal
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
ISSN: 1872-8952
Titre abrégé: Clin Neurophysiol
Pays: Netherlands
ID NLM: 100883319
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
09
12
2019
revised:
19
03
2020
accepted:
13
04
2020
pubmed:
11
5
2020
medline:
11
5
2021
entrez:
11
5
2020
Statut:
ppublish
Résumé
Priming non-invasive brain stimulation (NIBS) can improve motor learning in the elderly, but it remains unclear how benefits observed in a single training session translate to multiple training sessions. The current study therefore examined the influence of priming NIBS on acquisition and retention of a novel motor skill over sequential training days in older adults. In 30 older adults (68.2 ± 5.3 years, 14 females), paired-associative stimulation (PAS) was applied prior to visuomotor training on 3 consecutive days. The interstimulus interval used for PAS was either 10 ms (PAS During training, skill progressively increased across sessions (P < 0.0001), but this was not different between PAS PAS While multisession priming with PAS can influence long-term skill retention, improving skill acquisition requires investigation of alternative protocols.
Identifiants
pubmed: 32388475
pii: S1388-2457(20)30151-6
doi: 10.1016/j.clinph.2020.04.010
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1497-1507Informations de copyright
Copyright © 2020 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest None of the authors have potential conflicts of interest to be disclosed.