Urticaria: recommendations from the Italian Society of Allergology, Asthma and Clinical Immunology and the Italian Society of Allergological, Occupational and Environmental Dermatology.

Acute urticaria Angioedema Antihistamines Chronic urticaria Corticosteroids Guidelines Omalizumab

Journal

Clinical and molecular allergy : CMA
ISSN: 1476-7961
Titre abrégé: Clin Mol Allergy
Pays: England
ID NLM: 101152195

Informations de publication

Date de publication:
2020
Historique:
received: 23 05 2019
accepted: 25 04 2020
entrez: 12 5 2020
pubmed: 12 5 2020
medline: 12 5 2020
Statut: epublish

Résumé

Urticaria is a disorder affecting skin and mucosal tissues characterized by the occurrence of wheals, angioedema or both, the latter defining the urticaria-angioedema syndrome. It is estimated that 12-22% of the general population has suffered at least one subtype of urticaria during life, but only a small percentage (estimated at 7.6-16%) has acute urticaria, because it is usually self-limited and resolves spontaneously without requiring medical attention. This makes likely that its incidence is underestimated. The epidemiological data currently available on chronic urticaria in many cases are deeply discordant and not univocal, but a recent Italian study, based on the consultation of a national registry, reports a prevalence of chronic spontaneous urticaria of 0.02% to 0.4% and an incidence of 0.1-1.5 cases/1000 inhabitants/year. We reviewed the recent international guidelines about urticaria and we described a methodologic approach based on classification, pathophysiology, impact on quality of life, diagnosis and prognosis, differential diagnosis and management of all the types of urticaria. The aim of the present document from the Italian Society of Allergology, Asthma and Clinical Immunology (SIAAIC) and the Italian Society of Allergological, Occupational and Environmental Dermatology (SIDAPA) is to provide updated information to all physicians involved in diagnosis and management of urticaria and angioedema.

Sections du résumé

BACKGROUND BACKGROUND
Urticaria is a disorder affecting skin and mucosal tissues characterized by the occurrence of wheals, angioedema or both, the latter defining the urticaria-angioedema syndrome. It is estimated that 12-22% of the general population has suffered at least one subtype of urticaria during life, but only a small percentage (estimated at 7.6-16%) has acute urticaria, because it is usually self-limited and resolves spontaneously without requiring medical attention. This makes likely that its incidence is underestimated. The epidemiological data currently available on chronic urticaria in many cases are deeply discordant and not univocal, but a recent Italian study, based on the consultation of a national registry, reports a prevalence of chronic spontaneous urticaria of 0.02% to 0.4% and an incidence of 0.1-1.5 cases/1000 inhabitants/year.
METHODS METHODS
We reviewed the recent international guidelines about urticaria and we described a methodologic approach based on classification, pathophysiology, impact on quality of life, diagnosis and prognosis, differential diagnosis and management of all the types of urticaria.
CONCLUSIONS CONCLUSIONS
The aim of the present document from the Italian Society of Allergology, Asthma and Clinical Immunology (SIAAIC) and the Italian Society of Allergological, Occupational and Environmental Dermatology (SIDAPA) is to provide updated information to all physicians involved in diagnosis and management of urticaria and angioedema.

Identifiants

pubmed: 32390768
doi: 10.1186/s12948-020-00123-8
pii: 123
pmc: PMC7201804
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

8

Informations de copyright

© The Author(s) 2020.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare that they have no competing interests.

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Auteurs

Eustachio Nettis (E)

1Department of Emergency and Organ Transplantation, School and Chair of Allergology and Clinical Immunology, University of Bari - Aldo Moro, Bari, Italy.

Caterina Foti (C)

2Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari, Bari, Italy.

Marina Ambrifi (M)

3San Gallicano Dermatological Institute -IRCCS, Rome, Italy.

Ilaria Baiardini (I)

4Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.

Leonardo Bianchi (L)

5Section of Dermatology, Department of Medicine, University of Perugia, Perugia, Italy.

Alessandro Borghi (A)

6Section of Dermatology, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

Marco Caminati (M)

7Asthma Center and Allergy Unit, University of Verona and General Hospital, Verona, Italy.

Giorgio Walter Canonica (GW)

4Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
8Personalized Medicine, Asthma and Allergy, IRCCS Humanitas, Rozzano, Milan, Italy.

Marco Casciaro (M)

9School and Division of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.

Laura Colli (L)

10Department of Biomedical, Surgical and Dental Sciences, Clinical Dermatology, IRCCS Galeazzi Orthopaedic Institute, University of Milan, Milan, Italy.

Giselda Colombo (G)

11Unit of Immunology, Rheumatology Allergy and Rare Diseases, IRCCS Ospedale San Raffaele, Milan, Italy.

Monica Corazza (M)

6Section of Dermatology, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

Antonio Cristaudo (A)

3San Gallicano Dermatological Institute -IRCCS, Rome, Italy.

Giulia De Feo (G)

12Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy.

Ornella De Pita' (O)

13Clinical Pathology and Immune Inflammatory Disease of the Skin, Cristo Re Hospital, Rome, Italy.

Mario Di Gioacchino (M)

14Department of Medicine and Science on Ageing, School of Medicine, G. d'Annunzio University, Chieti-Pescara, Italy.

Elisabetta Di Leo (E)

Section of Allergy and Clinical Immunology, Unit of Internal Medicine, "F. Miulli" Hospital, Strada Provinciale per Santeramo Km 4.100, Acquaviva Delle Fonti (BA), Italy.

Filippo Fassio (F)

Allergy and Clinical Immunology Unit, Azienda USL Toscana Centro, Florence, Italy.

Sebastiano Gangemi (S)

9School and Division of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.

Alessia Gatta (A)

14Department of Medicine and Science on Ageing, School of Medicine, G. d'Annunzio University, Chieti-Pescara, Italy.

Katharina Hansel (K)

5Section of Dermatology, Department of Medicine, University of Perugia, Perugia, Italy.

Enrico Heffler (E)

4Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
8Personalized Medicine, Asthma and Allergy, IRCCS Humanitas, Rozzano, Milan, Italy.

Cristoforo Incorvaia (C)

Cardiac/Pulmonary Rehabilitation, ASST Pini-CTO, Milan, Italy.

Maddalena Napolitano (M)

18Section of Dermatology, Department of Medicine and Health Sciences Vincenzo Tiberio, University of Molise, Campobasso, Italy.

Cataldo Patruno (C)

19Department of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.

Silvia Peveri (S)

Allergy Department Unit, Piacenza Hospital, Piacenza, Italy.

Paolo Daniele Pigatto (PD)

10Department of Biomedical, Surgical and Dental Sciences, Clinical Dermatology, IRCCS Galeazzi Orthopaedic Institute, University of Milan, Milan, Italy.

Cristina Quecchia (C)

21Centro "Io e l'Asma", Ospedale dei Bambini, ASST Spedali Civili, Brescia, Italy.

Anna Radice (A)

22Immunoallergology Unit, Careggi University Hospital, Florence, Italy.

Giuseppe Alvise Ramirez (GA)

11Unit of Immunology, Rheumatology Allergy and Rare Diseases, IRCCS Ospedale San Raffaele, Milan, Italy.

Paolo Romita (P)

2Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari, Bari, Italy.

Franco Rongioletti (F)

Dermatological Clinic/UC of Dermatology, Department of Medical Science and Public Health, AOU Cagliari, Cagliari, Italy.

Oliviero Rossi (O)

22Immunoallergology Unit, Careggi University Hospital, Florence, Italy.

Eleonora Savi (E)

Allergy Department Unit, Piacenza Hospital, Piacenza, Italy.

Gianenrico Senna (G)

7Asthma Center and Allergy Unit, University of Verona and General Hospital, Verona, Italy.

Massimo Triggiani (M)

12Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy.

Myriam Zucca (M)

Dermatological Clinic/UC of Dermatology, Department of Medical Science and Public Health, AOU Cagliari, Cagliari, Italy.

Enrico Maggi (E)

24Department of Experimental and Clinical Medicine and Center of Excellence for Research, Transfer and High Education DENOTHE of the University of Florence, Florence, Italy.

Luca Stingeni (L)

5Section of Dermatology, Department of Medicine, University of Perugia, Perugia, Italy.

Classifications MeSH