Osteoradionecrosis of the Maxilla: Conservative Management and Reconstructive Considerations.
free flap reconstruction
management of osteoradionecrosis
maxillary osteonecrosis
maxillary osteoradionecrosis
Journal
Seminars in plastic surgery
ISSN: 1535-2188
Titre abrégé: Semin Plast Surg
Pays: United States
ID NLM: 101131275
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
entrez:
12
5
2020
pubmed:
12
5
2020
medline:
12
5
2020
Statut:
ppublish
Résumé
The implementation of radiotherapy in the multimodal treatment of advanced head and neck cancer has greatly improved survival rates. In some patients, however, this benefit comes at the potential expense of the tissue surrounding the primary site of malignancy. Osteoradionecrosis (ORN) of the facial bones, in particular the maxilla, is a debilitating complication of radiation therapy. Exposure to ionizing radiation results in devitalization of underlying bone with necrosis of adjacent soft tissue. Controversy surrounding appropriate early intervention in ORN persists and no consensus for clinical treatment has been established. In the present article, we review the pathophysiology of maxillary ORN and discuss the role of both conservative medical therapy and reconstruction.
Identifiants
pubmed: 32390778
doi: 10.1055/s-0040-1709144
pii: 01241
pmc: PMC7202910
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
106-113Informations de copyright
© Thieme Medical Publishers.
Déclaration de conflit d'intérêts
Conflicts of Interest None.
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