Recent Advances and Promises in Nitrile Hydratase: From Mechanism to Industrial Applications.
Nitrile hydratase
catalytic mechanism
gene types
industrial application
natural distribution
post-translational modification
selectivity
thermostability
Journal
Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513
Informations de publication
Date de publication:
2020
2020
Historique:
received:
31
12
2019
accepted:
30
03
2020
entrez:
12
5
2020
pubmed:
12
5
2020
medline:
12
5
2020
Statut:
epublish
Résumé
Nitrile hydratase (NHase, EC 4.2.1.84) is one type of metalloenzyme participating in the biotransformation of nitriles into amides. Given its catalytic specificity in amide production and eco-friendliness, NHase has overwhelmed its chemical counterpart during the past few decades. However, unclear catalytic mechanism, low thermostablity, and narrow substrate specificity limit the further application of NHase. During the past few years, numerous studies on the theoretical and industrial aspects of NHase have advanced the development of this green catalyst. This review critically focuses on NHase research from recent years, including the natural distribution, gene types, posttranslational modifications, expression, proposed catalytic mechanism, biochemical properties, and potential applications of NHase. The developments of NHase described here are not only useful for further application of NHase, but also beneficial for the development of the fields of biocatalysis and biotransformation.
Identifiants
pubmed: 32391348
doi: 10.3389/fbioe.2020.00352
pmc: PMC7193024
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
352Informations de copyright
Copyright © 2020 Cheng, Xia and Zhou.
Références
Appl Microbiol Biotechnol. 2007 Mar;74(3):535-9
pubmed: 17216468
Biotechnol J. 2007 Jun;2(6):717-24
pubmed: 17330219
Appl Environ Microbiol. 1988 Apr;54(4):1030-2
pubmed: 16347598
J Mol Graph Model. 2008 Nov;27(4):529-35
pubmed: 18948044
Mol Biol Rep. 2019 Aug;46(4):4661-4673
pubmed: 31201677
Appl Biochem Biotechnol. 2016 Apr;178(8):1481-7
pubmed: 26686500
Appl Biochem Biotechnol. 2019 Feb;187(2):439-448
pubmed: 29971551
PLoS One. 2017 Jun 23;12(6):e0179833
pubmed: 28644864
Int Microbiol. 2020 May;23(2):225-232
pubmed: 31410668
Biochemistry. 2003 Oct 14;42(40):11642-50
pubmed: 14529274
FEMS Microbiol Lett. 2014 Mar;352(1):38-44
pubmed: 24417729
Chem Biol. 2002 Jun;9(6):673-7
pubmed: 12079778
Bioresour Technol. 2015 Jun;185:28-34
pubmed: 25746475
Biotechnol Bioeng. 2019 Mar;116(3):481-489
pubmed: 30418672
Trends Biotechnol. 2008 Jan;26(1):32-8
pubmed: 18037176
J Biol Chem. 2016 Apr 8;291(15):7822-9
pubmed: 26865634
World J Microbiol Biotechnol. 1990 Jun;6(2):83-108
pubmed: 24429979
Cell. 2013 Apr 11;153(2):461-70
pubmed: 23582331
Genes Cells. 1997 Jan;2(1):13-28
pubmed: 9112437
Sci Rep. 2016 Jan 12;6:19183
pubmed: 26755342
Biochem J. 2017 Jan 15;474(2):247-258
pubmed: 27807009
J Agric Food Chem. 2019 May 29;67(21):5922-5931
pubmed: 31067049
Metallomics. 2013 Jun;5(7):804-7
pubmed: 23708681
J Biosci Bioeng. 2014 Sep;118(3):249-52
pubmed: 24698299
Biochemistry. 2001 Jul 10;40(27):7984-91
pubmed: 11434767
Org Biomol Chem. 2011 Apr 21;9(8):3011-9
pubmed: 21380438
FEBS Lett. 2003 Oct 23;553(3):391-6
pubmed: 14572657
J Biotechnol. 2015 Jun 10;203:9-16
pubmed: 25796588
J Biol Inorg Chem. 2010 Jun;15(5):655-65
pubmed: 20221653
Mar Drugs. 2013 Aug 21;11(8):3046-67
pubmed: 23966036
Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4352-7
pubmed: 21368207
Science. 1991 Nov 29;254(5036):1374-7
pubmed: 1962196
Int J Biol Macromol. 2020 Feb 1;144:19-28
pubmed: 31830454
Biosci Biotechnol Biochem. 1996 Sep;60(9):1391-400
pubmed: 8987584
Methods Enzymol. 2011;487:545-74
pubmed: 21187238
Molecules. 2020 Jan 06;25(1):
pubmed: 31935987
Crit Rev Biotechnol. 2017 Feb;37(1):69-81
pubmed: 26700071
J Bacteriol. 2008 Jun;190(12):4210-7
pubmed: 18408036
Angew Chem Int Ed Engl. 2015 Sep 7;54(37):10763-7
pubmed: 26333053
J Am Chem Soc. 2011 Mar 23;133(11):3954-63
pubmed: 21351789
Biochemistry. 2013 Mar 12;52(10):1788-1801
pubmed: 24449932
Nat Struct Biol. 1998 May;5(5):347-51
pubmed: 9586994
BMC Biotechnol. 2013 Jun 03;13:48
pubmed: 23731949
Adv Biochem Eng Biotechnol. 2009;113:33-77
pubmed: 19475377
Appl Microbiol Biotechnol. 2018 Sep;102(18):7891-7900
pubmed: 29998413
Biochem Biophys Res Commun. 2003 Dec 12;312(2):340-5
pubmed: 14637142
Appl Microbiol Biotechnol. 2002 Oct;60(1-2):33-44
pubmed: 12382040
Arch Biochem Biophys. 2018 Nov 1;657:1-7
pubmed: 30205086
BMC Bioinformatics. 2006 Jun 22;7:316
pubmed: 16792811
Mol Microbiol. 2010 May;76(3):545-58
pubmed: 20374493
Inorg Chem. 2017 Nov 6;56(21):13390-13400
pubmed: 29058882
Mol Microbiol. 2007 Aug;65(3):828-38
pubmed: 17635193
Endocrinology. 2012 Feb;153(2):954-60
pubmed: 22234466
PLoS One. 2012;7(4):e32867
pubmed: 22505998
Microbiology (Reading). 2013 Nov;159(Pt 11):2294-2302
pubmed: 24002749
Microb Cell Fact. 2012 Oct 30;11:142
pubmed: 23106943
Biochem Biophys Res Commun. 2014 Jul 18;450(1):401-8
pubmed: 24944015
Enzyme Microb Technol. 2001 Jul 5;29(1):20-27
pubmed: 11427231
Biochemistry. 1996 Dec 24;35(51):16777-81
pubmed: 8988015
Appl Microbiol Biotechnol. 2005 Jun;67(5):664-70
pubmed: 15668757
Appl Biochem Biotechnol. 2017 Aug;182(4):1458-1466
pubmed: 28150192
Metallomics. 2019 Jun 19;11(6):1162-1171
pubmed: 31111126
Nanoscale. 2020 Jan 2;12(2):967-972
pubmed: 31840718
FEBS Lett. 2000 Jan 14;465(2-3):173-7
pubmed: 10631329
3 Biotech. 2018 May;8(5):225
pubmed: 29713581
J Biol Chem. 2009 May 29;284(22):14930-8
pubmed: 19346246
Acc Chem Res. 2015 Mar 17;48(3):602-11
pubmed: 25699471
Biotechnol Bioeng. 2018 Mar;115(3):524-535
pubmed: 29080350
Appl Microbiol Biotechnol. 1998 May;49(5):568-72
pubmed: 9650255
J Biotechnol. 2012 Dec 15;164(2):354-62
pubmed: 23384947
Curr Opin Chem Biol. 2010 Apr;14(2):130-7
pubmed: 20083424
J Biosci Bioeng. 2017 Dec;124(6):641-646
pubmed: 28734701
J Evol Biol. 2008 Nov;21(6):1852-60
pubmed: 18717747
Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14849-54
pubmed: 18809911
J Microbiol Biotechnol. 2016 Feb;26(2):337-46
pubmed: 26562693
J Phys Chem B. 2016 Apr 7;120(13):3259-66
pubmed: 27007978
J Biol Inorg Chem. 2015 Jul;20(5):885-94
pubmed: 26077812
J Biol Chem. 2007 Mar 9;282(10):7397-404
pubmed: 17150969
Enzyme Microb Technol. 2018 Oct;117:9-14
pubmed: 30037557
J Mol Endocrinol. 2008 Apr;40(4):185-98
pubmed: 18372407
Protein Sci. 2000 May;9(5):1024-30
pubmed: 10850812
Chem Rev. 2004 Feb;104(2):509-25
pubmed: 14871133
Biochim Biophys Acta. 2005 Aug 30;1725(1):35-46
pubmed: 15955632
Mol Biol Evol. 2010 Dec;27(12):2879-89
pubmed: 20627874
Appl Environ Microbiol. 2000 Apr;66(4):1634-8
pubmed: 10742253
PLoS One. 2012;7(11):e50829
pubmed: 23226397
Org Biomol Chem. 2016 May 11;14(19):4393-9
pubmed: 27116228
PLoS One. 2008;3(12):e3976
pubmed: 19096720
Eur J Biochem. 2004 Jan;271(2):429-38
pubmed: 14717710
J Mol Biol. 2007 Mar 9;366(5):1497-509
pubmed: 17222425
Structure. 1997 May 15;5(5):691-9
pubmed: 9195885
Angew Chem Int Ed Engl. 2011 Jan 3;50(1):138-74
pubmed: 20715024
J Inorg Biochem. 2000 Jul 1;80(3-4):283-8
pubmed: 11001100
Chem Rev. 1996 Nov 7;96(7):2239-2314
pubmed: 11848828
Bioorg Med Chem. 1999 Oct;7(10):2239-45
pubmed: 10579532
Appl Microbiol Biotechnol. 1997 Dec;48(6):704-8
pubmed: 9457799
Inorg Chem. 2016 Jan 19;55(2):566-72
pubmed: 26699874
J Biotechnol. 2017 Jun 10;251:38-46
pubmed: 28323014
Appl Microbiol Biotechnol. 2020 Feb;104(3):1001-1012
pubmed: 31858190
J Am Chem Soc. 2014 Jan 29;136(4):1186-9
pubmed: 24383915
Science. 2003 Nov 21;302(5649):1364-8
pubmed: 14631033
Inorg Chem. 2007 Jun 11;46(12):4850-6
pubmed: 17497847
Appl Microbiol Biotechnol. 2008 Jan;77(5):985-93
pubmed: 17957365
J Mol Evol. 2009 Sep;69(3):240-8
pubmed: 19669682
BMC Biotechnol. 2016 Feb 20;16:21
pubmed: 26897378
Biotechnol Adv. 2010 Nov-Dec;28(6):725-41
pubmed: 20685247
J Biol Chem. 1997 Aug 22;272(34):21312-6
pubmed: 9261143
Inorg Chem. 2014 Mar 17;53(6):2760-2
pubmed: 24597943
Biochemistry. 2010 Nov 9;49(44):9638-48
pubmed: 20886813