Clinical Significance of an m6A Reader Gene,
N6-methyladenosine (m6A)
head and neck squamous cell carcinoma (HNSCC)
insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
prognostic factor
tumor
Journal
Frontiers in molecular biosciences
ISSN: 2296-889X
Titre abrégé: Front Mol Biosci
Pays: Switzerland
ID NLM: 101653173
Informations de publication
Date de publication:
2020
2020
Historique:
received:
04
02
2020
accepted:
26
03
2020
entrez:
12
5
2020
pubmed:
12
5
2020
medline:
12
5
2020
Statut:
epublish
Résumé
The importance of N6-methyladenosine (m6A) in tumor recurrence and prognosis has been recognized in recent years. The role of m6A readers, such as insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2), in regulating head and neck squamous cell carcinoma (HNSCC) remains unclear. We, therefore, assessed the prognostic role of IGF2BP2 in HNSCC using openly available data from The Cancer Genome Atlas (TCGA) in conjunction with HNSCC patient sample immunohistochemistry (
Identifiants
pubmed: 32391379
doi: 10.3389/fmolb.2020.00068
pmc: PMC7193208
doi:
Types de publication
Journal Article
Langues
eng
Pagination
68Informations de copyright
Copyright © 2020 Deng, Jiang, Liu and Chen.
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