[Lifestyle, genetics and the risk of dementia].

Leefstijl, genetica en het risico op dementie.
Dementia / genetics Genetic Predisposition to Disease Healthy Lifestyle Humans Life Style Preventive Health Services / ethics Risk Reduction Behavior

Journal

Nederlands tijdschrift voor geneeskunde
ISSN: 1876-8784
Titre abrégé: Ned Tijdschr Geneeskd
Pays: Netherlands
ID NLM: 0400770

Informations de publication

Date de publication:
19 03 2020
Historique:
entrez: 12 5 2020
pubmed: 12 5 2020
medline: 19 12 2020
Statut: epublish

Résumé

An unhealthy lifestyle increases the risk of dementia. Two observational studies explored whether targeted health and lifestyle interventions could attenuate or even offset increased genetic risk. Results from these observational studies are inconclusive. However, after the age of 60, favourable lifestyle behaviours may have less impact in groups with high genetic risk. This might inspire researchers and clinicians to determine genetic risk prior to offering preventive interventions. However, this raises important ethical concerns and practical difficulties. Lifestyle interventions should take place irrespective of genetically determined risk of dementia.

Identifiants

PMID: 32392016
pubmed: 32392016
pii:

Types de publication

Journal Article

Langues

dut

Sous-ensembles de citation

IM

Auteurs

Edo Richard (E)

Radboudumc, Donders Institutefor Brain, Cognition and Behaviour, afd. Neurologie, Nijmegen.
Contact: Edo Richard (Edo.Richard@radboudumc.nl).

Jan Willem van Dalen (JW)

Radboudumc, Donders Institutefor Brain, Cognition and Behaviour, afd. Neurologie, Nijmegen.

Eric Moll van Charante (E)

Amsterdam UMC, locatie AMC, afd. Huisartsgeneeskunde/Sociale Geneeskunde, Amsterdam.

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Classifications MeSH

questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › [Lifestyle, genetics and the risk of dementia].
questionsmedicales.fr › Phénomènes génétiques › Génotype › Prédisposition génétique à une maladie › [Lifestyle, genetics and the risk of dementia].
questionsmedicales.fr › Comportement et mécanismes comportementaux › Mode de vie › Mode de vie sain › [Lifestyle, genetics and the risk of dementia].
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › [Lifestyle, genetics and the risk of dementia].
questionsmedicales.fr › Comportement et mécanismes comportementaux › Mode de vie › [Lifestyle, genetics and the risk of dementia].
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Services de santé › Services de médecine préventive › [Lifestyle, genetics and the risk of dementia].
questionsmedicales.fr › Comportement et mécanismes comportementaux › Comportement › Comportement de réduction des risques › [Lifestyle, genetics and the risk of dementia].