Glucose biosensor based on open-source wireless microfluidic potentiostat.
Enzyme-based biosensor
IoT
Microfluidic biosensor
Open-source
Smartphone
Wireless
Journal
Sensors and actuators. B, Chemical
ISSN: 0925-4005
Titre abrégé: Sens Actuators B Chem
Pays: Switzerland
ID NLM: 101149755
Informations de publication
Date de publication:
01 Jul 2019
01 Jul 2019
Historique:
entrez:
13
5
2020
pubmed:
13
5
2020
medline:
13
5
2020
Statut:
ppublish
Résumé
Wireless potentiostats capable of cyclic voltammetry and amperometry that connect to the Internet are emerging as key attributes of future point-of-care devices. This work presents an "integrated microfluidic electrochemical detector" (iMED) three-electrode multi-potentiostat designed around operational amplifiers connected to a powerful WiFi-based microcontroller as a promising alternative to more expensive and complex strategies reported in the literature. The iMED is integrated with a microfluidic system developed to be controlled by the same microcontroller. The iMED is programmed wirelessly over a standard WiFi network and all electrochemical data is uploaded to an open-source cloud-based server. A wired desktop computer is not necessary for operation or program uploading. This method of integrated microfluidic automation is simple, uses common and inexpensive materials, and is compatible with commercial sample injectors. An integrated biosensor platform contains four screen-printed carbon arrays inside 4 separate microfluidic detection chambers with Pt counter and pseudo Ag/AgCl reference electrodes in situ. The iMED is benchmarked with K
Identifiants
pubmed: 32395016
doi: 10.1016/j.snb.2019.02.031
pmc: PMC7213535
mid: NIHMS1579054
doi:
Types de publication
Journal Article
Langues
eng
Pagination
616-624Subventions
Organisme : NIBIB NIH HHS
ID : R01 EB016707
Pays : United States
Références
Biosens Bioelectron. 2018 Feb 15;100:533-540
pubmed: 28988118
J Chem Educ. 2016 Jul 12;93(7):1316-1319
pubmed: 27453587
Electrophoresis. 2014 Aug;35(16):2370-7
pubmed: 24823494
Biosens Bioelectron. 2014 Dec 15;62:249-54
pubmed: 25016332
J Am Chem Soc. 2001 Sep 5;123(35):8630-1
pubmed: 11525685
Chem Rev. 2004 Oct;104(10):4867-86
pubmed: 15669171
Am J Physiol Endocrinol Metab. 2016 Oct 1;311(4):E661-E670
pubmed: 27530231
Biosens Bioelectron. 2012 Feb 15;32(1):309-13
pubmed: 22209069
Nat Commun. 2010 Apr 12;1:2
pubmed: 20975669
J Am Chem Soc. 2003 Apr 23;125(16):4951-7
pubmed: 12696915
Electrophoresis. 2012 Sep;33(17):2650-9
pubmed: 22965708
Nat Protoc. 2010 Nov;5(11):1844-56
pubmed: 21030959
PLoS One. 2015 Oct 28;10(10):e0140349
pubmed: 26510100
Biosens Bioelectron. 2013 Oct 15;48:188-96
pubmed: 23685315
Anal Chem. 1993 Dec 1;65(23):3512-7
pubmed: 8297033
Lab Chip. 2013 Aug 7;13(15):2950-5
pubmed: 23689554
Langmuir. 2014 Mar 25;30(11):3217-22
pubmed: 24625256
Lab Chip. 2014 Oct 21;14(20):4085-92
pubmed: 25182078
Sci Rep. 2016 Apr 21;6:24598
pubmed: 27098564
Biosens Bioelectron. 2013 May 15;43:30-7
pubmed: 23274194
Lab Chip. 2015 Apr 21;15(8):1934-41
pubmed: 25738695
Sensors (Basel). 2017 Aug 12;17(8):
pubmed: 28805693
Lab Chip. 2011 Feb 21;11(4):733-7
pubmed: 21132206
Biosens Bioelectron. 2011 Jul 15;26(11):4477-83
pubmed: 21632234
Anal Chem. 2016 Jan 5;88(1):320-38
pubmed: 26599485
Anal Chem. 2018 May 15;90(10):6240-6246
pubmed: 29658268
Biosens Bioelectron. 2015 Nov 15;73:32-40
pubmed: 26043313
Anal Chem. 2017 Sep 5;89(17):8643-8649
pubmed: 28741350
Biosens Bioelectron. 2017 Jan 15;87:522-530
pubmed: 27598854
Behav Res Methods. 2012 Jun;44(2):305-13
pubmed: 22037977
Anal Chem. 2005 Aug 1;77(15):4726-33
pubmed: 16053282
Anal Chem. 2016 Feb 16;88(4):2156-63
pubmed: 26750758
Phys Chem Chem Phys. 2012 Nov 14;14(42):14667-72
pubmed: 23033161
Trends Biotechnol. 2014 Jul;32(7):347-50
pubmed: 24954000
Anal Chem. 2015 Apr 21;87(8):4472-8
pubmed: 25821929
Anal Chem. 2008 Sep 1;80(17):6472-9
pubmed: 18754652
PLoS One. 2014 Sep 17;9(9):e107216
pubmed: 25229451
Talanta. 2015 Oct 1;143:178-183
pubmed: 26078146
Front Chem. 2014 Aug 27;2:63
pubmed: 25221775
Lab Chip. 2015 Jun 21;15(12):2584-7
pubmed: 25968976
Lab Chip. 2017 Jan 31;17(3):484-489
pubmed: 28067370
Biomed Microdevices. 2015 Aug;17(4):82
pubmed: 26227212
Nat Commun. 2011 Jun 28;2:370
pubmed: 21712818
Lab Chip. 2016 Jul 7;16(13):2450-8
pubmed: 27242064
Lab Chip. 2014 Aug 7;14(15):2762-77
pubmed: 24903572
Biosens Bioelectron. 2014 Mar 15;53:268-74
pubmed: 24144557
Nat Rev Immunol. 2012 Feb 17;12(3):191-200
pubmed: 22343568
Nature. 2006 Jul 27;442(7101):368-73
pubmed: 16871203
Chem Soc Rev. 2010 Mar;39(3):1153-82
pubmed: 20179830
Biosens Bioelectron. 2018 Jul 1;110:78-88
pubmed: 29602034
Lab Chip. 2013 May 21;13(10):1911-8
pubmed: 23529280
Biosens Bioelectron. 2007 Mar 15;22(8):1694-9
pubmed: 16962762
Lab Chip. 2009 Jan 7;9(1):79-86
pubmed: 19209338
Lab Chip. 2013 Jan 7;13(1):171-8
pubmed: 23160342
PLoS One. 2011;6(9):e23783
pubmed: 21931613
Nature. 2014 Mar 13;507(7491):181-9
pubmed: 24622198
Biosens Bioelectron. 2014 Jul 15;57:284-91
pubmed: 24607579
J Am Chem Soc. 2003 May 28;125(21):6588-94
pubmed: 12785800
Anal Chem. 1995 Apr 15;67(8):1332-8
pubmed: 7741213
Lab Chip. 2012 Oct 21;12(20):3930-5
pubmed: 22814625
Analyst. 2013 Jan 7;138(1):171-8
pubmed: 23095952
Biosens Bioelectron. 2017 Apr 15;90:475-480
pubmed: 27825524
Lab Chip. 2009 Jun 7;9(11):1548-55
pubmed: 19458861
Talanta. 2018 Jan 15;177:163-170
pubmed: 29108571
Anal Chem. 2013 Jun 4;85(11):5304-10
pubmed: 23635325