Imitation dynamics in the mitigation of the novel coronavirus disease (COVID-19) outbreak in Wuhan, China from 2019 to 2020.
Coronavirus disease 2019 (COVID-19)
final epidemic size
imitation game
mathematical modelling
reproduction number
Journal
Annals of translational medicine
ISSN: 2305-5839
Titre abrégé: Ann Transl Med
Pays: China
ID NLM: 101617978
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
entrez:
13
5
2020
pubmed:
13
5
2020
medline:
13
5
2020
Statut:
ppublish
Résumé
The coronavirus disease 2019 (COVID-19) was first identified in Wuhan, China on December 2019 in patients presenting with atypical pneumonia. Although 'city-lockdown' policy reduced the spatial spreading of the COVID-19, the city-level outbreaks within each city remain a major concern to be addressed. The local or regional level disease control mainly depends on individuals self-administered infection prevention actions. The contradiction between choice of taking infection prevention actions or not makes the elimination difficult under a voluntary acting scheme, and represents a clash between the optimal choice of action for the individual interest and group interests. We develop a compartmental epidemic model based on the classic susceptible-exposed-infectious-recovered model and use this to fit the data. Behavioral imitation through a game theoretical decision-making process is incorporated to study and project the dynamics of the COVID-19 outbreak in Wuhan, China. By varying the key model parameters, we explore the probable course of the outbreak in terms of size and timing under several public interventions in improving public awareness and sensitivity to the infection risk as well as their potential impact. We estimate the basic reproduction number, Through an imitating social learning process, individual-level behavioral change on taking infection prevention actions have the potentials to significantly reduce the COVID-19 outbreak in terms of size and timing at city-level. Timely and substantially resources and supports for improving the willingness-to-act and conducts of self-administered infection prevention actions are recommended to reduce to the COVID-19 associated risks.
Sections du résumé
BACKGROUND
BACKGROUND
The coronavirus disease 2019 (COVID-19) was first identified in Wuhan, China on December 2019 in patients presenting with atypical pneumonia. Although 'city-lockdown' policy reduced the spatial spreading of the COVID-19, the city-level outbreaks within each city remain a major concern to be addressed. The local or regional level disease control mainly depends on individuals self-administered infection prevention actions. The contradiction between choice of taking infection prevention actions or not makes the elimination difficult under a voluntary acting scheme, and represents a clash between the optimal choice of action for the individual interest and group interests.
METHODS
METHODS
We develop a compartmental epidemic model based on the classic susceptible-exposed-infectious-recovered model and use this to fit the data. Behavioral imitation through a game theoretical decision-making process is incorporated to study and project the dynamics of the COVID-19 outbreak in Wuhan, China. By varying the key model parameters, we explore the probable course of the outbreak in terms of size and timing under several public interventions in improving public awareness and sensitivity to the infection risk as well as their potential impact.
RESULTS
RESULTS
We estimate the basic reproduction number,
CONCLUSIONS
CONCLUSIONS
Through an imitating social learning process, individual-level behavioral change on taking infection prevention actions have the potentials to significantly reduce the COVID-19 outbreak in terms of size and timing at city-level. Timely and substantially resources and supports for improving the willingness-to-act and conducts of self-administered infection prevention actions are recommended to reduce to the COVID-19 associated risks.
Identifiants
pubmed: 32395492
doi: 10.21037/atm.2020.03.168
pii: atm-08-07-448
pmc: PMC7210122
doi:
Types de publication
Journal Article
Langues
eng
Pagination
448Informations de copyright
2020 Annals of Translational Medicine. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/atm.2020.03.168). Dr. He reports grants from Alibaba (China), during the conduct of the study. The other authors have no conflicts of interest to declare.
Références
Lancet. 2020 Feb 15;395(10223):514-523
pubmed: 31986261
N Engl J Med. 2020 Mar 26;382(13):1199-1207
pubmed: 31995857
Emerg Infect Dis. 2005 Jul;11(7):1142-5
pubmed: 16022801
Travel Med Infect Dis. 2019 Jan - Feb;27:27-32
pubmed: 30550839
Sci Rep. 2017 Mar 21;7(1):273
pubmed: 28325935
Innovation (Camb). 2020 Nov 25;1(3):100048
pubmed: 33521762
Euro Surveill. 2020 Jan;25(3):
pubmed: 31992388
Euro Surveill. 2020 Jan;25(4):
pubmed: 32019669
Ann Intern Med. 2012 Feb 7;156(3):173-81
pubmed: 22312137
Epidemiology. 2009 May;20(3):344-7
pubmed: 19279492
J Clin Med. 2020 Feb 01;9(2):
pubmed: 32024089
Proc Biol Sci. 2005 Aug 22;272(1573):1669-75
pubmed: 16087421
Am J Epidemiol. 1986 Dec;124(6):1012-20
pubmed: 3096132
Stat Methods Med Res. 2018 Jul;27(7):1968-1978
pubmed: 29846148
Science. 2003 Jun 20;300(5627):1966-70
pubmed: 12766207
Ann Intern Med. 2020 Apr 21;172(8):567-568
pubmed: 32023340
Lancet. 2020 Feb 29;395(10225):689-697
pubmed: 32014114
J Travel Med. 2020 Mar 13;27(2):
pubmed: 31943059
BMJ. 2020 Jan 20;368:m236
pubmed: 31959587
Int J Infect Dis. 2020 Mar;92:214-217
pubmed: 32007643
Travel Med Infect Dis. 2020 Jan - Feb;33:101568
pubmed: 32006656
J Clin Med. 2020 Feb 17;9(2):
pubmed: 32079150
Epidemiology. 2005 Nov;16(6):791-801
pubmed: 16222170
Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13391-4
pubmed: 15329411
Math Biosci. 2002 Nov-Dec;180:29-48
pubmed: 12387915
J Travel Med. 2020 Mar 13;27(2):
pubmed: 32080723
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
J R Soc Interface. 2010 Feb 6;7(43):271-83
pubmed: 19535416
Philos Trans R Soc Lond B Biol Sci. 2021 Jul 19;376(1829):20200265
pubmed: 34053269
Ann Intern Med. 2009 Oct 6;151(7):437-46
pubmed: 19652172
J Clin Med. 2020 Feb 04;9(2):
pubmed: 32033064
Sci Rep. 2017 Mar 14;7:44122
pubmed: 28290504
J Theor Biol. 2018 Oct 7;454:1-10
pubmed: 29792875