Recurrent fungal endophthalmitis after intravitreal injections of bevacizumab.

Bevacizumab Fungal endophthalmitis Intravitreal injections Saccharomyces cervisiae

Journal

American journal of ophthalmology case reports
ISSN: 2451-9936
Titre abrégé: Am J Ophthalmol Case Rep
Pays: United States
ID NLM: 101679941

Informations de publication

Date de publication:
Mar 2020
Historique:
received: 08 03 2019
revised: 26 11 2019
accepted: 02 01 2020
entrez: 13 5 2020
pubmed: 13 5 2020
medline: 13 5 2020
Statut: epublish

Résumé

We intend to describe an uncommon case of recurrent post-cataract fungal endophthalmitis after intravitreal injections of Bevacizumab. A 73-year-old male, who underwent an uncomplicated cataract surgery 8 months ago, presented to our department with postoperative endophthalmitis 5 days after his fifth intravitreal injection (IVI) of bevacizumab for treatment of cystoid macula edema caused by central retinal venous occlusion 6 months ago. The visual acuity (VA) was 0.1 (20/200). The patient underwent an emergency pars plana vitrectomy. Culture of vitreous tap was negative. Eight weeks later, the patient presented again with recurrent endophthalmitis 2 days after his sixth IVI of bevacizumab. VA was hand motion. The patient was treated with an emergency anterior and posterior segment washout with intracapsular posterior intraocular lens (pIOL) extraction. Culture of pIOL revealed we assume that this is a rare case of chronic late-onset post-cataract fungal endophthalmitis, which was activated by repeated intravitreal injections of Bevacizumab.

Identifiants

pubmed: 32395665
doi: 10.1016/j.ajoc.2020.100591
pii: S2451-9936(19)30129-X
pii: 100591
pmc: PMC7206407
doi:

Types de publication

Case Reports

Langues

eng

Pagination

100591

Informations de copyright

© 2020 The Authors.

Déclaration de conflit d'intérêts

All authors have no financial disclosures.

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Auteurs

Alaa Din Abdin (AD)

Department of Ophthalmology, Saarland University Medical Center UKS, 66421, Homburg/Saar, Germany.

Shady Suffo (S)

Department of Ophthalmology, Saarland University Medical Center UKS, 66421, Homburg/Saar, Germany.

Dina Alnaggar (D)

Department of Ophthalmology, Saarland University Medical Center UKS, 66421, Homburg/Saar, Germany.

Loay Daas (L)

Department of Ophthalmology, Saarland University Medical Center UKS, 66421, Homburg/Saar, Germany.

Berthold Seitz (B)

Department of Ophthalmology, Saarland University Medical Center UKS, 66421, Homburg/Saar, Germany.

Classifications MeSH