Peptide-based formula versus standard-based polymeric formula for critically ill children: is it superior for patients' tolerance?
critically ill children
feeding
peptide-based
standard formula
Journal
Archives of medical science : AMS
ISSN: 1734-1922
Titre abrégé: Arch Med Sci
Pays: Poland
ID NLM: 101258257
Informations de publication
Date de publication:
2020
2020
Historique:
received:
22
04
2017
accepted:
17
08
2017
entrez:
14
5
2020
pubmed:
14
5
2020
medline:
14
5
2020
Statut:
epublish
Résumé
Malnutrition affects 50% of hospitalized children and 25-70% of critically ill children. Enteral tube feeding is generally considered the preferred modality for critically ill pediatric patients. Clinical advantages of using peptide-based formulas are still controversial in critically ill children. The aim of this study was to compare the effect of a peptide-based formula versus a standard polymeric formula on feeding tolerance and whether this will affect the outcome among critically ill children. This single blind case control study was conducted on 180 randomly selected critically ill children in the pediatric critical care unit (PICU) of Ain Shams University. Patients were divided into 2 groups: a group receiving a standard polymeric formula (group 1; 90 patients) and a group receiving a peptide-based formula (group II; 90 patients). Nutritional requirements, days to reach full enteral feeding, feeding intolerance symptoms and anthropometric measurements were recorded for all patients at admission together with their pediatric risk of mortality score (PRISM). Length of PICU stay, occurrence of sepsis together with survival were analyzed at discharge as outcome measures. Patients receiving a peptide-based formula showed a significant decrease in feeding interruptions and abdominal distention ( Peptide-based formula feeding was better tolerated than standard polymeric formula feeding in critically ill pediatric patients. However, the choice of patients receiving the peptide-based formula needs to be further evaluated.
Identifiants
pubmed: 32399107
doi: 10.5114/aoms.2020.94157
pii: 40260
pmc: PMC7212209
doi:
Types de publication
Journal Article
Langues
eng
Pagination
592-596Informations de copyright
Copyright: © 2020 Termedia & Banach.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Am J Gastroenterol. 2000 Nov;95(11):3044-52
pubmed: 11095317
Acta Anaesthesiol Scand. 2009 Mar;53(3):318-24
pubmed: 19243317
Clin Nutr. 2017 Jun;36(3):706-709
pubmed: 27161892
World J Gastrointest Surg. 2016 Oct 27;8(10):700-705
pubmed: 27830042
Crit Care Med. 2001 Oct;29(10):1955-61
pubmed: 11588461
JPEN J Parenter Enteral Nutr. 2006 Jan-Feb;30(1):1-5
pubmed: 16387891
Nutr Clin Pract. 2010 Feb;25(1):16-25
pubmed: 20130154
J Pediatr Gastroenterol Nutr. 2012 May;54(5):620-3
pubmed: 22249807
An Pediatr (Barc). 2005 Feb;62(2):105-12
pubmed: 15701304
Nutr Clin Pract. 2006 Aug;21(4):411-5
pubmed: 16870811