Ulcerative colitis: Recent advances in the understanding of disease pathogenesis.
Inflammation
Inflammatory Bowel Disease
Mucosal Immunology
Pathogenesis
Ulcerative colitis
Journal
F1000Research
ISSN: 2046-1402
Titre abrégé: F1000Res
Pays: England
ID NLM: 101594320
Informations de publication
Date de publication:
2020
2020
Historique:
accepted:
15
04
2020
entrez:
14
5
2020
pubmed:
14
5
2020
medline:
14
7
2020
Statut:
epublish
Résumé
Inflammatory bowel diseases are common, complex, immune-mediated conditions with a sharply rising global prevalence. While major advances since 2000 have provided strong mechanistic clues implicating a de-regulation in the normal interaction among host genetics, immunity, microbiome, and the environment, more recent progress has generated entirely new hypotheses and also further refined older disease concepts. In this review, we focus specifically on these novel developments in the pathogenesis of ulcerative colitis.
Identifiants
pubmed: 32399194
doi: 10.12688/f1000research.20805.1
pmc: PMC7194476
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright: © 2020 Porter RJ et al.
Déclaration de conflit d'intérêts
No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.
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